Postoperative cognitive disorders.
Terri G. Monk,Catherine C. Price +1 more
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TLDR
There is emerging evidence that decreased preoperative cognitive function contributes to the development of postoperative delirium and POCD, and Randomized controlled trials evaluating interventions to improve long-term cognitive outcomes in elderly patients are urgently needed.Abstract:
Purpose of review
The elderly are the fastest growing segment of the population and undergo 25–30% of all surgical procedures. Postoperative cognitive problems are common in older patients following major surgery. The socioeconomic implications of these cognitive disorders are profound; cognitive decline is associated with a loss of independence, a reduction in the quality of life, and death. This review will focus on the two most common cognitive problems following surgery: postoperative delirium and postoperative cognitive dysfunction (POCD).read more
Citations
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Lasting impact of general anaesthesia on the brain: mechanisms and relevance.
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Impact of intraoperative hypotension and blood pressure fluctuations on early postoperative delirium after non-cardiac surgery
TL;DR: Investigating whether intraoperative hypotension was associated with postoperative delirium in older patients undergoing major non-cardiac surgery showed that increased blood pressure fluctuation, not absolute or relative hypotension, was predictive of postoperativedelirium.
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Обґрунтування концепції безперервного вдосконалення національної системи охорони здоров’я України
К.О. Надутий,Київ Патронатна служба Верховної Ради України,В.М. Лехан,І.В. Найда,Державний заклад «Дніпропетровська медична академія Моз України»,Київ Громадська cпілка «Центр інновацій «Сходи в майбутнє» +5 more
TL;DR: In this article, the authors present a discussion on the state of the art in the field of public discussion.http://moz.gov.ua/public-discussions/proektnakazu-ministerstva-ohoroni-zdorovja-ukraini-dejaki-pitannja-vedennja-veternja-veernjausnovkiv-v-elektronnij-sistemi-head-of-government/index.html
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Inflammatory markers in postoperative delirium (POD) and cognitive dysfunction (POCD): A meta-analysis of observational studies.
Xuling Liu,Yang Yu,Shengmei Zhu +2 more
TL;DR: In this article, the similarities and differences in inflammatory biomarkers in postoperative delirium (POD) and cognitive dysfunction (POCD) were summarized and discussed, and the aim of the study was to summarize and discuss the similarities.
References
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Journal ArticleDOI
Clarifying Confusion: The Confusion Assessment Method: A New Method for Detection of Delirium
TL;DR: The CAM is sensitive, specific, reliable, and easy to use for identification of delirium and was shown to have convergent agreement with four other mental status tests, including the Mini-Mental State Examination.
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Journal ArticleDOI
Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study
J. T. Moller,Pjm Pierre Cluitmans,Lars S. Rasmussen,Peter J. Houx,H Rasmussen,Jaume Canet,Patrick Rabbitt,Jellemer Jolles,K. Larsen,CD Hanning,Olivier Langeron,T Johnson,PM Lauven,P A Kristensen,A Biedler,H van Beem,O Fraidakis,Jeffrey H. Silverstein,Jew Jan Beneken,JS Gravenstein +19 more
TL;DR: The findings of this international multicentre study have implications for studies of the causes of cognitive decline and, in clinical practice, for the information given to patients before surgery.
Journal ArticleDOI
Delirium in older persons.
TL;DR: This review summarizes the clinical manifestations of and risk factors for delirium and the evaluation of patients with this condition and provides guidance regarding practical measures to prevent this common complication.
Journal ArticleDOI
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.
Richard R. Riker,Yahya Shehabi,Paula M. Bokesch,Daniel Ceraso,Wayne Wisemandle,Firas Koura,Patrick Whitten,Benjamin D. Margolis,Daniel W. Byrne,E. Wesley Ely,Marcelo G. Rocha +10 more
TL;DR: At comparable sedation levels, dexmedetomidine-treated patients spent less time on the ventilator, experienced less delirium, and developed less tachycardia and hypertension.