Potential Health Benefit of Garlic Based on Human Intervention Studies: A Brief Overview.
Johura Ansary,Tamara Y. Forbes-Hernandez,Emilio Gil,Danila Cianciosi,Jiaojiao Zhang,Maria Elexpuru-Zabaleta,Jesus Simal-Gandara,Francesca Giampieri,Francesca Giampieri,Francesca Giampieri,Maurizio Battino,Maurizio Battino,Maurizio Battino +12 more
TLDR
The present review aims to provide a comprehensive overview on the consumption of garlic, garlic preparation, garlic extract, and garlic extract-derived bioactive constituents on oxidative stress, inflammation, cancer, cardiovascular and metabolic disorders, skin, bone, and other common diseases.Abstract:
Garlic is a polyphenolic and organosulfur enriched nutraceutical spice consumed since ancient times. Garlic and its secondary metabolites have shown excellent health-promoting and disease-preventing effects on many human common diseases, such as cancer, cardiovascular and metabolic disorders, blood pressure, and diabetes, through its antioxidant, anti-inflammatory, and lipid-lowering properties, as demonstrated in several in vitro, in vivo, and clinical studies. The present review aims to provide a comprehensive overview on the consumption of garlic, garlic preparation, garlic extract, and garlic extract-derived bioactive constituents on oxidative stress, inflammation, cancer, cardiovascular and metabolic disorders, skin, bone, and other common diseases. Among the 83 human interventional trials considered, the consumption of garlic has been reported to modulate multiple biomarkers of different diseases; in addition, its combination with drugs or other food matrices has been shown to be safe and to prolong their therapeutic effects. The rapid metabolism and poor bioavailability that have limited the therapeutic use of garlic in the last years are also discussed.read more
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Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials
Shokoh Parham,Anousheh Zargar Kharazi,Hamid Reza Bakhsheshi-Rad,Hamid Reza Bakhsheshi-Rad,Hadi Nur,Ahmad Fauzi Ismail,Safian Sharif,Seeram Ramakrishna,Filippo Berto +8 more
TL;DR: In this paper, the authors highlight the antibacterial, antiviral, and radical scavenger (antioxidant) properties of herbal materials, including clove, portulaca, tribulus, eryngium, cinnamon, turmeric, ginger, thyme, pennyroyal, mint, fennel, chamomile, burdock, eucalyptus, primrose, lemon balm, mallow, and garlic.
Journal ArticleDOI
Anticancer potential of garlic and its bioactive constituents: A systematic and comprehensive review.
Danielle De Greef,Emily M. Barton,Elise N. Sandberg,Courtney R. Croley,Joshua Pumarol,Tin Lok Wong,Niranjan Das,Anupam Bishayee +7 more
TL;DR: The intent of this literature research is to explore the potential of garlic-derived products and bioactive organosulfur compounds as cancer chemopreventive and chemotherapeutic agents and concerns and limitations that have arisen in past studies regarding standards of measurement, bioavailability, and method of delivery are addressed.
Journal ArticleDOI
The role of natural antioxidants in cisplatin-induced hepatotoxicity.
Norhashima Abd Rashid,Syarifah Aisyah Syed Abd Halim,Seong Lin Teoh,Siti Balkis Budin,Farida Hussan,Nurul Raudzah Adib Ridzuan,Nahdia Afiifah Abdul Jalil +6 more
TL;DR: In this article, a review concentrated on the protective role of several natural products, which has been proven in the laboratory findings to combat cisplatin-induced hepatotoxicity, and demonstrated that treatment with honey and royal jelly was demonstrated to decrease serum transaminases and scavenge free radicals in the liver.
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Drug Delivery of Natural Products Through Nanocarriers for Effective Breast Cancer Therapy: A Comprehensive Review of Literature
Journal ArticleDOI
Association between Oral Cancer and Diet: An Update.
Jesús Rodríguez-Molinero,Blanca del Carmen Migueláñez-Medrán,Cristina Puente-Gutiérrez,Esther Delgado-Somolinos,Carmen Martín Carreras-Presas,Javier Fernández-Farhall,Antonio Francisco López-Sánchez +6 more
TL;DR: The main limitation of in vivo studies is the complexity of isolating the effects related to each one of the nutrients and the relationship with other possible etiological mechanisms as mentioned in this paper. On the contrary, in vitro studies allow determining the specific mechanisms of action of some of the dietary compounds.
References
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