Practical steps to improving the management of type 1 diabetes: recommendations from the Global Partnership for Effective Diabetes Management
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TLDR
The Global Partnership for Effective Diabetes Management as mentioned in this paper provides practical recommendations to help improve the care of patients with type 1 diabetes, including reaching glycaemic goals, overcoming the reality and fear of hypoglycaemia, and appropriate insulin therapy and dose adjustment.Abstract:
The Diabetes Control and Complications Trial (DCCT) led to considerable improvements in the management of type 1 diabetes, with the wider adoption of intensive insulin therapy to reduce the risk of complications. However, a large gap between evidence and practice remains, as recently shown by the Pittsburgh Epidemiology of Diabetes Complications (EDC) study, in which 30-year rates of microvascular complications in the 'real world' EDC patients were twice that of DCCT patients who received intensive insulin therapy. This gap may be attributed to the many challenges that patients and practitioners face in the day-to-day management of the disease. These barriers include reaching glycaemic goals, overcoming the reality and fear of hypoglycaemia, and appropriate insulin therapy and dose adjustment. As practitioners, the question remains: how do we help patients with type 1 diabetes manage glycaemia while overcoming barriers? In this article, the Global Partnership for Effective Diabetes Management provides practical recommendations to help improve the care of patients with type 1 diabetes.read more
Citations
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Diabetes Self-Management Smartphone Application for Adults With Type 1 Diabetes: Randomized Controlled Trial
TL;DR: In adjunct to usual care, the use of a diabetes-related smartphone application combined with weekly text-message support from a health care professional can significantly improve glycemic control in adults with type 1 diabetes.
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Intensive glucose control versus conventional glucose control for type 1 diabetes mellitus
TL;DR: Assessment of the effects of intensive versus conventional glycaemic targets in patients with type 1 diabetes in terms of long-term complications and whether very low, near normoglycaemic values are of additional benefit found evidence for an initial worsening of retinopathy.
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Efficacy and Safety of Canagliflozin, a Sodium–Glucose Cotransporter 2 Inhibitor, as Add-on to Insulin in Patients With Type 1 Diabetes
TL;DR: Canagliflozin provided reductions in HbA1c, body weight, and insulin dose with no increase in hypoglycemia, but increased rates of ketone-related AEs, including DKA, in adults with type 1 diabetes inadequately controlled with insulin.
Journal ArticleDOI
Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study
Hood Thabit,Alexandra Lubina-Solomon,Marietta Stadler,Lalantha Leelarathna,Emma Walkinshaw,A Pernet,Janet M. Allen,Ahmed Iqbal,Pratik Choudhary,Kavita Kumareswaran,Marianna Nodale,Chloe Nisbet,Malgorzata E. Wilinska,Katharine D. Barnard,David B. Dunger,Simon Heller,Stephanie A. Amiel,Mark L. Evans,Roman Hovorka +18 more
TL;DR: Unsupervised overnight closed-loop insulin delivery at home is feasible and could improve glucose control in adults with type 1 diabetes.
Journal ArticleDOI
Single- and Dual-Hormone Artificial Pancreas for Overnight Glucose Control in Type 1 Diabetes.
Ahmad Haidar,Rémi Rabasa-Lhoret,Laurent Legault,Leif E. Lovblom,Rohan Rakheja,Virginie Messier,Émilie D'Aoust,C. Marcelo Falappa,Tara Justice,Andrej Orszag,Holly Tschirhart,Maryse Dallaire,Martin Ladouceur,Bruce A. Perkins,Bruce A. Perkins +14 more
TL;DR: Although the dual-hormone configuration did not increase overnight time-in-target glucose levels, an effect on lowering hypoglycemia risk cannot be ruled out.
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