Journal ArticleDOI
Prebiotics and other microbial substrates for gut functionality.
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TLDR
This work has shown that modulation of the intestinal microbiota by exogenous and endogenous substrates can be expected to improve various physiological functions of the body, not just those in the intestine.About:
This article is published in Current Opinion in Biotechnology.The article was published on 2005-04-01. It has received 194 citations till now.read more
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Effects of Probiotics, Prebiotics, and Synbiotics on Human Health.
TL;DR: This paper provides a review of available information and summarises the current knowledge on the effects of probiotics, prebiotics, and synbiotics on human health, and verified study results proving their efficacy in human nutrition are presented.
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Next-generation beneficial microbes : The case of Akkermansia muciniphila
TL;DR: It is proposed that microbes and microbiomegnosy, or knowledge of the authors' gut microbiome, can become a novel source of future therapies as plants and its related knowledge have been the source for designing drugs over the last century.
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Lactobacillus plantarum—survival, functional and potential probiotic properties in the human intestinal tract
TL;DR: This review discusses the studies of the safety and survival of L. plantarum in the human intestinal tract, the effects of this bacterium on the host and it provides an overview of the molecular studies addressing the activity ofL.
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Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention.
TL;DR: The epidemiology and pathophysiology of NEC is reviewed, with an emphasis on the latest research findings and potential areas for future research.
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Microbial Metabolic Networks at the Mucus Layer Lead to Diet-Independent Butyrate and Vitamin B12 Production by Intestinal Symbionts.
Clara Belzer,Loo Wee Chia,Steven Aalvink,Bhawani Chamlagain,Vieno Piironen,Jan Knol,Willem M. de Vos,Willem M. de Vos +7 more
TL;DR: The observed metabolic interactions between A. muciniphila and butyrogenic bacterial taxa support the existence of colonic vitamin and butyrate production pathways that are dependent on host glycan production and independent of dietary carbohydrates.
References
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Dietary Modulation of the Human Colonic Microbiota: Introducing the Concept of Prebiotics
TL;DR: By combining the rationale of pro- and prebiotics, the concept of synbiotics is proposed to characterize some colonic foods with interesting nutritional properties that make these compounds candidates for classification as health-enhancing functional food ingredients.
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Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides
TL;DR: Resistant starch is a prebiotic, but knowledge of its other interactions with the microflora is limited and the contribution of RS to fermentation and colonic physiology seems to be greater than that of NSP.
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How host-microbial interactions shape the nutrient environment of the mammalian intestine
TL;DR: This paper showed that Bacteroides thetaiotaomicron, a prominent and genetically manipulatable component of the normal human and mouse gut, modifies many aspects of intestinal cellular differentiation/gene expression to benefit both host and microbe.
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Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium.
TL;DR: According to the data obtained in this work, strain MucT represents a novel bacterium belonging to a new genus in subdivision 1 of the Verrucomicrobia; the name Akkermansia muciniphila gen. nov., sp.
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The interaction between bacteria and bile
TL;DR: The antimicrobial actions of bile are described, the variations in bile tolerance between bacterial genera are assessed and the relationship between bile and virulence is examined.