Predictors of the progression of renal disease in the Modification of Diet in Renal Disease Study
Lawrence G. Hunsicker,Sharon Adler,Arlene W. Caggiula,Brian K. England,Tom Greene,John W. Kusek,Nancy L. Rogers,Paul E. Teschan,Gerald J. Beck +8 more
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TLDR
A systematic analysis to determine baseline factors that predict the decline in GFR, or which alter the efficacy of the diet or blood pressure interventions, found an approximately linear mean GFR decline as renal disease progresses.About:
This article is published in Kidney International.The article was published on 1997-06-01 and is currently open access. It has received 670 citations till now. The article focuses on the topics: Renal function & Blood pressure.read more
Citations
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Journal ArticleDOI
Uric acid and cardiovascular risk.
TL;DR: This review summarizes relevant studies concerning uric acid and possible links to hypertension, renal disease, and cardiovascular disease and presents current evidence.
Journal ArticleDOI
Chronic Kidney Disease and Mortality Risk: A Systematic Review
Marcello Tonelli,Natasha Wiebe,Bruce F. Culleton,Andrew A. House,Chris Rabbat,Mei Fok,Finlay A. McAlister,Amit X. Garg +7 more
TL;DR: This review supports current guidelines that identify individuals with CKD as being at high risk for cardiovascular mortality and determines which interventions best offset this risk remains a health priority.
Journal ArticleDOI
The Metabolic Syndrome and Chronic Kidney Disease in U.S. Adults
Jing Chen,Paul Muntner,L Lee Hamm,Daniel W. Jones,Vecihi Batuman,Vivian Fonseca,Paul K. Whelton,Jiang He +7 more
TL;DR: The association between the metabolic syndrome and risk for chronic kidney disease and microalbuminuria in a large representative sample of U.S. adults who participated in the NHANES III was examined.
Journal ArticleDOI
Is There a Pathogenetic Role for Uric Acid in Hypertension and Cardiovascular and Renal Disease
Richard J. Johnson,Duk Hee Kang,Daniel I. Feig,Salah D. Kivlighn,John Kanellis,Susumu Watanabe,Katherine R. Tuttle,Bernardo Rodriguez-Iturbe,Jaime Herrera-Acosta,Marilda Mazzali +9 more
TL;DR: It is time to reevaluate the role of uric acid as a risk factor for cardiovascular disease and hypertension and to design human studies to address this controversy.
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Chronic Hypoxia and Tubulointerstitial Injury: A Final Common Pathway to End-Stage Renal Failure
TL;DR: Therapeutic approaches that target the chronic hypoxia should prove effective against a broad range of renal diseases, and current modalities include the improvement of anemia with erythropoietin, the preservation of peritubular capillary blood flow by blockade of the renin-angiotensin system, and the use of antioxidants.
References
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An introduction to the bootstrap
Bradley Efron,Robert Tibshirani +1 more
TL;DR: This article presents bootstrap methods for estimation, using simple arguments, with Minitab macros for implementing these methods, as well as some examples of how these methods could be used for estimation purposes.
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Random-effects models for longitudinal data
Nan M. Laird,James H. Ware +1 more
TL;DR: In this article, a unified approach to fitting two-stage random-effects models, based on a combination of empirical Bayes and maximum likelihood estimation of model parameters and using the EM algorithm, is discussed.
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An Introduction to the Bootstrap
TL;DR: Statistical theory attacks the problem from both ends as discussed by the authors, and provides optimal methods for finding a real signal in a noisy background, and also provides strict checks against the overinterpretation of random patterns.
Journal ArticleDOI
The Effects of Dietary Protein Restriction and Blood-Pressure Control on the Progression of Chronic Renal Disease
Saulo Klahr,Andrew S. Levey,Gerald J. Beck,Arlene W. Caggiula,Lawrence G. Hunsicker,John W. Kusek,Gary E. Striker +6 more
TL;DR: Restricting protein intake and controlling hypertension delay the progression of renal disease in animals and in patients with various chronic renal diseases.
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