Pregnancy in inflammatory bowel disease: Effect of sulfasalazine and corticosteroids on fetal outcome
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TLDR
Inflammatory bowel disease, except for severe active Crohn's disease, does not seem to affect the outcome of concurrent pregnancy adversely, and the use of corticosteroid and sulfasalazine in pregnancy associated with ulcerative colitis is unlikely to increase the fetal morbidity or mortality.About:
This article is published in Gastroenterology.The article was published on 1981-01-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Inflammatory bowel disease & Ulcerative colitis.read more
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The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations
Gert Van Assche,Axel Dignass,Walter Reinisch,C. Janneke van der Woude,Andreas Sturm,Martine De Vos,Mario Guslandi,Bas Oldenburg,Iris Dotan,Philippe Marteau,Alessandro Ardizzone,Daniel C. Baumgart,Geert R. D'Haens,Paolo Gionchetti,Francisco Portela,Boris Vucelić,Johan D. Söderholm,Johanna C. Escher,Sibylle Koletzko,Kaija-Leena Kolho,Milan Lukas,Christian Mottet,Herbert Tilg,Severine Vermeire,F. Carbonnel,Andrew T. Cole,Gottfried Novacek,Max Reinshagen,Epameinondas V. Tsianos,Klaus Herrlinger,Yoram Bouhnik,Ralf Kiesslich,Eduard F. Stange,Simon Travis,James O. Lindsay +34 more
TL;DR: The aim of this Consensus was therefore critically to evaluate the optimal strategies for the management of post-operative recurrence in CD.
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Birth defects after maternal exposure to corticosteroids: prospective cohort study and meta-analysis of epidemiological studies
Laura Y. Park-Wyllie,Paolo Mazzotta,Anne Pastuszak,Myla E Moretti,Lizanne Beique,Laura Hunnisett,Mark H. Friesen,Sheila Jacobson,S. Kasapinovic,Debra Chang,Orna Diav-Citrin,David Chitayat,Irena Nulman,Thomas R. Einarson,Gideon Koren +14 more
TL;DR: Although prednisone does not represent a major teratogenic risk in humans at therapeutic doses, it does increase by an order of 3.4-fold the risk of oral cleft, which is consistent with the existing animal studies.
Journal ArticleDOI
Anti-inflammatory and immunosuppressive drugs and reproduction.
Monika Østensen,Munther A. Khamashta,Michael D. Lockshin,Ann L. Parke,Antonio Brucato,Howard Carp,Andrea Doria,Raj Rai,Pier Luigi Meroni,Irene Cetin,Ronald H. W. M. Derksen,Ware Branch,Mario Motta,Caroline Gordon,Guillermo Ruiz-Irastorza,Arsenio Spinillo,Deborah I. Friedman,Rolando Cimaz,Andrew Czeizel,J.C. Piette,Ricard Cervera,Roger A. Levy,Maurizio Clementi,Sara De Carolis,Michelle Petri,Yehuda Shoenfeld,D Faden,Guido Valesini,Angela Tincani +28 more
TL;DR: Benefits of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed.
Journal ArticleDOI
Outcome of Pregnancy in Women Receiving Infliximab for the Treatment of Crohn's Disease and Rheumatoid Arthritis
Jeffry Katz,C Antoni,Gregory F Keenan,Deirdre E Smith,Stephen J. Jacobs,Gary R. Lichtenstein +5 more
TL;DR: It is suggested that infliximab exposure during pregnancy results in outcomes that do not differ from those in the U.S. population of pregnant women or pregnant women with CD not exposed to inflIXimab.
Journal ArticleDOI
European evidence based consensus on the diagnosis and management of Crohn's disease: special situations.
R. Caprilli,Miquel A. Gassull,Johanna C. Escher,Gabriele Moser,Pia Munkholm,Alastair Forbes,Daan W. Hommes,H. Lochs,Erika Angelucci,A. Cocco,Boris Vucelić,Hans Hildebrand,Sanja Kolaček,L. Riis,Milan Lukas,R. De Franchis,M. Hamilton,G. Jantschek,Pierre Michetti,Colm O'Morain,M. M. Anwar,J. L. Freitas,Ioannis A. Mouzas,Filip Baert,Rod Mitchell,Christopher J. Hawkey +25 more
TL;DR: The third section of the European Crohn's and Colitis Organisation (ECCO) Consensus on the management of Crohn disease concerns postoperative recurrence, fistulating disease, paediatrics, pregnancy, psychosomatics, extraintestinal manifestations, and alternative therapy.
References
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Journal ArticleDOI
National Cooperative Crohn's Disease Study: results of drug treatment.
Robert W. Summers,Donald M. Switz,John T. Sessions,Jack M. Becktel,William R. Best,Fred Kern,John W. Singleton +6 more
TL;DR: Patients' drug therapy immediately before entry to the study significantly affected subsequent response, and none of the drugs was superior to placebo in prophylaxis against flare-up or recurrence.
Journal ArticleDOI
An experiment to determine the active therapeutic moiety of sulphasalazine
TL;DR: It is concluded that the active therapeutic moiety of S.A.S.P. is a function of the parent molecule or of these two principal metabolites of sulphapyridine and 5-aminosalicylic acid.
Journal ArticleDOI
Prenatal Exposure to Prednisone in Humans and Animals Retards Intrauterine Growth
TL;DR: Prednisone treatment for infertility and subsequent pregnancy maintenance in humans resulted in a significant decrease in the birth weight of full-term infants and a marked increase in the percentage of newborn infants weighing 2500 grams or less, that is, "light for dates" in comparison to control offspring.
Journal ArticleDOI
A controlled therapeutic trial of long-term maintenance treatment of ulcerative colitis with sulphasalazine (Salazopyrin)
A. S. Dissanayake,S. C. Truelove +1 more
TL;DR: It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects.