Prevalence of thyroid nodules and their associated clinical parameters: a large-scale, multicenter-based health checkup study.
Jae Hoon Moon,Min Kyung Hyun,Ja Youn Lee,Jung Im Shim,Tae Hyuk Kim,Hoon Sung Choi,Hwa Young Ahn,Kyung Won Kim,Do Joon Park,Young Joo Park,Ka Hee Yi +10 more
TLDR
The high prevalence of thyroid nodules in people who underwent thyroid US at a health checkup suggests that increased detection of thyroid nodsules resulted in an increased prevalence in the general population, however, metabolic disturbances may also have contributed to the increase in thyroid nodule prevalence in Korea.Abstract:
Background/aims We evaluated the prevalence and characteristics of thyroid nodules detected by thyroid ultrasound (US) at health checkups and the associated clinical parameters. Methods A total of 72,319 subjects who underwent thyroid US at three health checkup centers in Korea from January 2004 to December 2010 were included in this study. The correlations between the presence of thyroid nodules and other clinical parameters were analyzed. Results The prevalence of thyroid nodules and cysts was 34.2% (n = 24,757). Thyroid nodules were more prevalent in women and older age groups. Among the subjects with thyroid nodules with size information (n = 24,686), 18,833 (76.3%) had nodules measuring ≤ 1.0 cm. Women and older age groups showed higher proportion of larger nodules. Percentage of women, age, body mass index (BMI), waist circumference, body fat composition, blood pressure, and the level of fasting glucose, total cholesterol, and low density lipoprotein cholesterol were higher in the subjects with thyroid nodules compared to those without nodules. The prevalence of metabolic syndrome and overt/subclinical thyrotoxic state was higher in the subjects with thyroid nodules. In the multivariable logistic regression analysis, women, age, BMI, metabolic syndrome, and thyrotoxicosis were independently associated with the presence of thyroid nodules. Conclusions The high prevalence of thyroid nodules in people who underwent thyroid US at a health checkup suggests that increased detection of thyroid nodules resulted in an increased prevalence in the general population. However, metabolic disturbances may also have contributed to the increase in thyroid nodule prevalence in Korea.read more
Citations
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Safety and efficacy of thermal ablation (radiofrequency and laser): should we treat all types of thyroid nodules? †
Adrien Ben Hamou,Edouard Ghanassia,Stéphanie Espiard,Henry Abi Rached,Arnaud Jannin,Jean Michel Correas,Christine Do Cao,Maeva Kyheng,Marie-Christine Vantyghem,Hervé Monpeyssen +9 more
TL;DR: A significant volumetric reduction was achieved with both techniques, regardless of nodule’s characteristics, at 18 months, andTransient but potentially serious adverse events were reported in 3% of patients.
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The role of an anti-diabetic drug metformin in the treatment of endocrine tumors
TL;DR: Repositioning of metformin has emerged as a promising strategy for adjuvant therapy of endocrine tumors and the mechanisms of synergy between met formin and other anti-cancer agents need to be elucidated further to guide well-designed prospective trials on combination therapies in endocrine malignancies.
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Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study
Hyemi Kwon,Jin Hyung Jung,Kyungdo Han,Yong Gyu Park,Jung Hwan Cho,Da Young Lee,Ji Min Han,Se Eun Park,Eun-Jung Rhee,Won Young Lee +9 more
TL;DR: This was the first nationwide study of the prevalence and annual incidence of thyroid nodules, hypothyroidism, and hyperthyroidism in Koreans to take into account recent changes and to include the current status of patients receiving treatment.
Journal ArticleDOI
The Association of Thyroid Nodules with Metabolic Status: A Cross-Sectional SPECT-China Study
Yi Chen,Chunfang Zhu,Yingchao Chen,Ningjian Wang,Qin Li,Bing Han,Li Zhao,Chi Chen,Hualing Zhai,Yingli Lu +9 more
TL;DR: The status of metabolic disorders might be associated with higher risks of TN in both genders, and in women, obesity, central obesity, and NAFLD might contribute to the development of a taller-than-wide nodule.
Journal ArticleDOI
Prevalence of Thyroid Nodules in China: A Health Examination Cohort-Based Study.
TL;DR: Wang et al. as discussed by the authors investigated the prevalence of thyroid nodules in a healthy Chinese population and found that thyroid nodule was a common clinical problem and some are potentially cancerous.
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