Journal ArticleDOI
Profilin: A relevant aeroallergen?
Monica Ruiz-Garcia,Manuela García del Potro,Mar Fernández-Nieto,Domingo Barber,Lucía Jimeno-Nogales,Joaquín Sastre +5 more
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This work was made possible in part by grant 1KL2R, R025006-01 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and the NIH Roadmap for Medical Research.Abstract:
From the Divisions of Pediatric Allergy and Immunology and Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Md; and the Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md. E-mail: ckeet1@jhmi.edu. The study described was made possible in part by grant 1KL2R, R025006-01 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and the NIH Roadmap for Medical Research. Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NCRR or NIH. Information on NCRR is available at http://www.ncrr.nih. gov/. Information on Re-engineering the Clinical Research Enterprise can be obtained from http://nihroadmap.nih.gov/clinicalresearch/overview-translational.asp. This work was also supported by the National Institute of Allergy and Infectious Disease (R01AI070630), the National Institute of Environmental Health Sciences (P50ES015903, P01 ES018176, K23ES016819) and the US Environmental Protection Agency (R82672401). Disclosure of potential conflict of interest: C. A. Keet and E. C. Matsui receive research support from the National Institutes of Health. The rest of the authors have declared that they have no conflict of interest.read more
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EAACI Molecular Allergology User's Guide.
Paolo Maria Matricardi,Jörg Kleine-Tebbe,Hans Jürgen Hoffmann,Rudolf Valenta,Christiane Hilger,Stephanie Hofmaier,Rob C. Aalberse,Ioana Agache,Riccardo Asero,Barbara Ballmer-Weber,Domingo Barber,Kirsten Beyer,Tilo Biedermann,M. B. Bilò,Simon Blank,Barbara Bohle,Philipp P. Bosshard,Heimo Breiteneder,Helen A. Brough,Luis Caraballo,J-C Caubet,Reto Crameri,Janet M. Davies,Nikolaos Douladiris,M. Ebisawa,Philippe Eigenmann,Montserrat Fernandez-Rivas,Fatima Ferreira,Gabriele Gadermaier,Martin Glatz,Robert G. Hamilton,Thomas Hawranek,P W Hellings,Karin Hoffmann-Sommergruber,Thilo Jakob,Uta Jappe,Marek Jutel,Sandip D. Kamath,Edward F. Knol,Peter Korošec,Annette Kuehn,Gideon Lack,Gideon Lack,Andreas L. Lopata,Mika J. Mäkelä,Martine Morisset,Verena Niederberger,Anna Nowak-Wegrzyn,Nikolaos G. Papadopoulos,Elide A. Pastorello,Gabrielle Pauli,Thomas A.E. Platts-Mills,Daniela Posa,Lars K. Poulsen,Monika Raulf,Joaquín Sastre,Enrico Scala,Johannes Schmid,Peter Schmid-Grendelmeier,M. van Hage,R. van Ree,Stefan Vieths,Richard W. Weber,Magnus Wickman,Antonella Muraro,Markus Ollert +65 more
TL;DR: The European Academy of Allergy and Clinical Immunology (EAACI) Molecular Allergology User's Guide (MAUG) as mentioned in this paper provides comprehensive information on important allergens and describes the diagnostic options using component-resolved diagnosis (CRD).
Journal ArticleDOI
A WAO - ARIA - GA²LEN consensus document on molecular-based allergy diagnostics.
Giorgio Walter Canonica,Ignacio J. Ansotegui,Ruby Pawankar,Peter Schmid-Grendelmeier,Marianne van Hage,Carlos E. Baena-Cagnani,Giovanni Melioli,Carlos Nunes,Giovanni Passalacqua,Lanny J. Rosenwasser,Hugh A. Sampson,Joaquín Sastre,Jean Bousquet,Torsten Zuberbier +13 more
TL;DR: The aim of this consensus document is to provide a practical guide for the indications, determination, and interpretation of MA diagnostics for clinicians trained in allergology.
Journal ArticleDOI
Influence of Heavy Metals (Ni, Cu, and Zn) on Nitro-Oxidative Stress Responses, Proteome Regulation and Allergen Production in Basil (Ocimum basilicum L.) Plants.
Egli C. Georgiadou,Ewa Kowalska,Katarzyna Patla,Kamila Kulbat,Beata Smolińska,Joanna Leszczyńska,Vasileios Fotopoulos +6 more
TL;DR: Ni stress in basil plants appears to be less damaging and with lower allergenic potential compared with Cu and Zn stress, while Cu-stressed basil plants experience most detrimental effects and display highest allergen production.
Journal ArticleDOI
Peamaclein - a new peach allergenic protein: similarities, differences and misleading features compared to Pru p 3
Lisa Tuppo,Claudia Alessandri,D. Pomponi,Delia Picone,Maurizio Tamburrini,Rosetta Ferrara,Milena Petriccione,Iolanda Mangone,Paola Palazzo,Marina Liso,Ivana Giangrieco,Roberta Crescenzo,Maria Livia Bernardi,Danila Zennaro,Manuela Helmer-Citterich,Adriano Mari,Maria Antonietta Ciardiello +16 more
TL;DR: Among the peach‐derived allergens which are already known, the lipid transfer protein (Pru p 3) seems to be the one to exert severe allergic reactions.
Journal ArticleDOI
Profilin as a severe food allergen in allergic patients overexposed to grass pollen.
TL;DR: The aim of the study was to evaluate the role ofprofilins as severe food allergens in allergic patients overexposed to grass who were referred for severe food reactions and were sensitized to profilins.
References
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Protein Measurement with the Folin Phenol Reagent
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Oral allergy syndrome: a clinical, diagnostic, and therapeutic challenge
TL;DR: OAS is a challenging diagnosis to the practicing allergist because of its many clinical, diagnostic, and therapeutic considerations, and understanding these challenges and their underlying mechanisms can facilitate a knowledgeable approach to treating an oral allergy patient.
Journal ArticleDOI
Component‐resolved diagnosis of pollen allergy based on skin testing with profilin, polcalcin and lipid transfer protein pan‐allergens
Domingo Barber,F de la Torre,Manuel Lombardero,I. Antépara,Carlos Colás,Ignacio Dávila,Ana I. Tabar,Carmen Vidal,Mayte Villalba,Gabriel Salcedo,R. Rodríguez +10 more
TL;DR: Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due to the existence of possible confounding factors in this type of patients.