Journal ArticleDOI
Protective effects of chlorogenic acid, curcumin and β-carotene against γ-radiation-induced in vivo chromosomal damage
TLDR
The results obtained suggest that oral administration of CGA, CR and BC to mice can significantly reduce the frequencies of micronucleated polychromatic erythrocytes induced by whole body exposure to γ-radiation.About:
This article is published in Mutation Research Letters.The article was published on 1993-11-01. It has received 139 citations till now. The article focuses on the topics: Micronucleus test.read more
Citations
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Journal Article
Anticancer potential of curcumin: preclinical and clinical studies.
TL;DR: Evidence has also been presented to suggest that curcumin can suppress tumor initiation, promotion and metastasis, and Pharmacologically,Curcumin has been found to be safe.
Book ChapterDOI
Curcumin: The Indian solid gold
TL;DR: Curcumin has been shown to exhibit antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities and thus has a potential against various malignant diseases, diabetes, allergies, arthritis, Alzheimer's disease, and other chronic illnesses.
Journal ArticleDOI
Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances.
TL;DR: Yakuchinone A and B and yakuchinone B present in Alpinia oxyphylla Miquel (Zingiberaceae) have inhibitory effects on phorbol ester-induced inflammation and skin carcinogenesis in mice, and oxidative stress in vitro.
Journal ArticleDOI
Protection against ionizing radiation by antioxidant nutrients and phytochemicals
TL;DR: Results from animal experiments indicate that antioxidant nutrients, such as vitamin E and selenium compounds, are protective against lethality and other radiation effects but to a lesser degree than most synthetic protectors.
Journal ArticleDOI
"Spicing up" of the immune system by curcumin.
TL;DR: Curcumin’s reported beneficial effects in arthritis, allergy, asthma, atherosclerosis, heart disease, Alzheimer's disease, diabetes, and cancer might be due in part to its ability to modulate the immune system, and these findings warrant further consideration of curcumin as a therapy for immune disorders.
References
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Journal ArticleDOI
Beta-carotene: an unusual type of lipid antioxidant
G. W. Burton,Keith U. Ingold +1 more
TL;DR: New experiments in vitro show that beta-carotene belongs to a previously unknown class of biological antioxidants, and exhibits good radical-trapping antioxidant behavior only at partial pressures of oxygen significantly less than 150 torr, the pressure of oxygen in normal air.
Journal Article
Inhibitory Effect of Curcumin, Chlorogenic Acid, Caffeic Acid, and Ferulic Acid on Tumor Promotion in Mouse Skin by 12-O-Tetradecanoylphorbol-13-acetate
TL;DR: The effects of topically applied curcumin, chlorogenic acid, caffeic acid, or ferulic acid on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced epidermal ornithine decarboxylase activity, epidersmal DNA synthesis, and the promotion of skin tumors were evaluated in female CD-1 mice.
Journal Article
Inhibition of neoplasia by minor dietary constituents
TL;DR: Induction of glutathione S-transferase activity is being used to detect the presence of blocking agents in complex natural products, in particular those that act by enhancing host detoxification systems.
Journal ArticleDOI
The beneficial and hazardous effects of simple phenolic compounds.
TL;DR: Phenolics have proved to be potent inhibitors of carcinogenesis at the initiation and promotion stages induced by carcinogens and promoters of different molecular structures, and these multiple, occasionally contradictory functions of simple phenolics make it difficult to propose their use as chemopreventive agents.