Pulmonary carcinosarcoma initially presenting as invasive aspergillosis: a case report of previously unreported combination
TLDR
A case of primary carcinosarcoma of the lung concurrently occurring with invasive pulmonary aspergillosis in a 66-year old patient is described.Abstract:
Carcinosarcoma of the lung is a malignant tumor composed of a mixture of carcinoma and sarcoma elements. The carcinomatous component is most commonly squamous followed by adenocarcinoma. The sarcomatous component commonly comprises the bulk of the tumor and shows poorly differentiated spindle cell features. Foci of differentiated sarcomatous elements such as chondrosarcoma and osteosarcoma may be seen. Aspergillus pneumonia is the most common form of invasive aspergillosis and occurs mainly in patients with malignancy, immunocompromizing or debilitating diseases. Patients with Aspergillus pneumonia present with fever, cough, chest pain and occasionally hemoptysis. Tissue examination is the most reliable method for diagnosis, and mortality rate is high. We describe a case of primary carcinosarcoma of the lung concurrently occurring with invasive pulmonary aspergillosis in a 66-year old patient.read more
Citations
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Pulmonary mycoses diagnosed using exfoliative cytology: infection or colonization?
Lavleen Singh,Deepali Jain,Karan Madan,Sandeep Mathur,Priti Chatterjee,Randeep Guleria,Venkateswaran K. Iyer +6 more
TL;DR: A 5-year retrospective analysis of all cases of pulmonary fungal infection diagnosed using exfoliative cytology for pulmonary mycoses found Aspergillus and Candida species are the most common fungal organisms.
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Pulmonary Carcinosarcoma: A Case Report of Biphasic Lung Tumor.
TL;DR: Carcinosarcoma is an unusual biphasic tumor of the lung with carcinomatous and sarcomatous components with a poorer prognosis than non-small cell lung carcinoma with focal spindle cell atypia in a 71-year-old female.
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Clinical features and prognostic factors of pulmonary carcinosarcoma: A nomogram development and validation based on surveillance epidemiology and end results database
TL;DR: A nomogram was constructed for PCS patients’ survival prediction by combining the independent risk factors, including gender, stage, surgery, radiation, and chemotherapy, and showed good discrimination, calibration, and predictive power in the training and validation sets.
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Carcinosarcoma of the Lung Associated with Tuberculosis
TL;DR: A case of 64-year-old male with carcinosarcoma of the lung associated with tuberculosis involvement of the same site shortly after successful treatment of tuberculosis is presented.
References
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Pathology and genetics of tumours of the lung , pleura, thymus and heart
TL;DR: This book will not become a unity of the way for you to get amazing benefits at all, but, it will serve something that will let you get the best time and moment to spend for reading the book.
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Aspergillosis complicating neoplastic disease.
TL;DR: The incidence of aspergillosis is increasing and should be considered in the setting of progressive pulmonary infiltrates in leukemic and other heavily immunosuppressed patients who respond poorly to antibacterial therapy.
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Factors Associated with Overall and Attributable Mortality in Invasive Aspergillosis
Yasmine Nivoix,Michel Velten,Valérie Letscher-Bru,Alireza Moghaddam,Shanti Natarajan-Amé,Cécile Fohrer,Bruno Lioure,Karin Bilger,Philippe Lutun,Luc Marcellin,Anne Launoy,Guy Freys,Jean-Pierre Bergerat,Raoul Herbrecht +13 more
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Current Approaches to Diagnosis and Treatment of Invasive Aspergillosis
Brahm H. Segal,Thomas J. Walsh +1 more
TL;DR: There is significant interest in combination antifungal therapy pairing an echinocandin with either an azole or amphotericin B formulation as therapy for invasive aspergillosis, and there has been an increased understanding of the immunology of Aspergillus infection.
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