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Random walks in biology
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This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know.Abstract:
This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know. It provides a sound basis for understanding random motions of molecules, subcellular particles, or cells, or of processes that depend on such motion or are markedly affected by it. Readers do not need to understand thermodynamics in order to acquire a knowledge of the physics involved in diffusion, sedimentation, electrophoresis, chromatography, and cell motility--subjects that become lively and immediate when the author discusses them in terms of random walks of individual particles.read more
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Journal ArticleDOI
Crawling and Gliding: A Computational Model for Shape-Driven Cell Migration.
TL;DR: The Cellular Potts Model is extended with an actin-inspired feedback mechanism that allows small stochastic cell rufflings to expand to cell protrusions, which produces realistically crawling and deforming amoeboid cells, and gliding half-moon shaped keratocyte-like cells.
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The thermal impulse response of Escherichia coli
Eli Paster,William S. Ryu +1 more
TL;DR: The thermal impulse response at temperatures < 31°C is similar to the chemotactic impulse response: Both follow a similar time course, share the same directionality, and show biphasic characteristics.
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Timing facilitated site transfer of an enzyme on DNA.
TL;DR: A new method where a small molecule trap (uracil) is used to clock a DNA repair enzyme as it hops and slides between damaged sites in DNA, which provides unprecedented information: the mean length for DNA sliding, the 1D sliding constant, the maximum hopping radius and time frame for DNA hopping events.
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Molecular photodynamics involved in multi-photon excitation fluorescence microscopy
TL;DR: In this article, a simple model for calculating the fluorescence generated by the multi-photon excitation (MPE) of molecules in solution is presented, which takes into account internal molecular dynamics such as ground-state depletion due to inter-system crossing (ISC), as well as external molecular dynamics associated with diffusion into and out of an excitation volume confined in 3-dimensions.
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Lévy flights search patterns of biological organisms
Gandhimohan. M. Viswanathan,Vsevolod Afanasyev,Sergey V. Buldyrev,Shlomo Havlin,Shlomo Havlin,M. G. E. da Luz,Ernesto P. Raposo,H. Eugene Stanley +7 more
TL;DR: The extent to which findings suggesting an inverse square probability density distribution P(l)∼l−2 of step lengths l leads to an optimal random search strategy for organisms that can search efficiently for randomly located objects that can only be detected in the limited vicinity of the searcher and can be revisited any number of times is explored.