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Random walks in biology
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This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know.Abstract:
This book is a lucid, straightforward introduction to the concepts and techniques of statistical physics that students of biology, biochemistry, and biophysics must know. It provides a sound basis for understanding random motions of molecules, subcellular particles, or cells, or of processes that depend on such motion or are markedly affected by it. Readers do not need to understand thermodynamics in order to acquire a knowledge of the physics involved in diffusion, sedimentation, electrophoresis, chromatography, and cell motility--subjects that become lively and immediate when the author discusses them in terms of random walks of individual particles.read more
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Journal ArticleDOI
Reversible Ca Gradients between the Subplasmalemma and Cytosol Differentially Activate Ca-dependent Cl Currents
Khaled Machaca,H. Criss Hartzell +1 more
TL;DR: Xenopus oocytes express several different Ca-activated Cl currents that have different waveforms and biophysical properties, and it is hypothesized that very local, transient, reversible Ca gradients develop between the subplasmalemmal space and the bulk cytosol.
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Microhydrodynamics, Brownian Motion, and Complex Fluids
TL;DR: In this article, the authors introduce the dynamics of fluids at small scales, the physical and mathematical underpinnings of Brownian motion, and the application of these subjects to the dynamics and flow of complex fluids such as colloidal suspensions and polymer solutions.
Journal ArticleDOI
Reduced Efficiency of Magnetotaxis in Magnetotactic Coccoid Bacteria in Higher than Geomagnetic Fields
Yongxin Pan,Wei Lin,Jinhua Li,Wenfang Wu,Lanxiang Tian,Chenglong Deng,Qingsong Liu,Rixiang Zhu,Michael Winklhofer,Nikolai Petersen +9 more
TL;DR: It turns out that the contribution of the field-parallel migration velocity of magnetotactic bacteria decreases with increasing field strength from 0.1 to 1.5 mT, suggesting that magnetotaxis is optimized under geomagnetic field conditions.
Journal ArticleDOI
Population-level transcription cycles derive from stochastic timing of single-cell transcription.
Tatjana Degenhardt,Katja N. Rybakova,Aleksandra Tomaszewska,Aleksandra Tomaszewska,Martijn J. Moné,Hans V. Westerhoff,Hans V. Westerhoff,Frank J. Bruggeman,Frank J. Bruggeman,Carsten Carlberg,Carsten Carlberg +10 more
TL;DR: In this article, the authors constructed a detailed stochastic model for single-gene transcription at the molecular level using realistic kinetics for diffusion and protein complex dynamics, and proposed that the cyclic nature of population gene expression is primarily based on the intrinsic periodicity of the transcription process itself.
Journal ArticleDOI
How Large Should Whales Be
Aaron Clauset,Aaron Clauset +1 more
TL;DR: Strong agreement between theory and data suggests that a universal macroevolutionary tradeoff governs body size evolution for all mammals, regardless of their habitat.