Journal ArticleDOI
Recovery of normal topography in the somatosensory cortex of monkeys after nerve crush and regeneration.
TLDR
After median nerve fibers to glabrous skin on the hands of monkeys were crushed and allowed to regenerate, normal topographical organization was recovered in the representation of the hand in primary somatosensory cortex.Abstract:
After median nerve fibers to glabrous skin on the hands of monkeys were crushed and allowed to regenerate, normal topographical organization was recovered in the representation of the hand in primary somatosensory cortex. Similar recovery of normal cortical organization may underlie the sensory restoration that usually follows nerve crush injury in humans.read more
Citations
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Plasticity of sensory and motor maps in adult mammals.
TL;DR: This rev iew addresses questions about the capacity of sensory and motor maps in the brains of adul t mammals to change as a resul t of alterations in the effectiveness of inputs, the availability of effectors, and direct damage.
Journal ArticleDOI
Neural plasticity after peripheral nerve injury and regeneration.
TL;DR: An important direction for ongoing research is the development of therapeutic strategies that enhance axonal regeneration, promote selective target reinnervation, but are also able to modulate central nervous system reorganization, amplifying those positive adaptive changes that help to improve functional recovery but also diminishing undesirable consequences.
Journal ArticleDOI
Nervous system reorganization following injury.
TL;DR: While cross-modal plasticity appears to be useful in enhancing the perceptions of compensatory sensory modalities, the functional significance of motor reorganization following peripheral injury remains unclear and some forms of sensory reorganization may even be associated with deleterious consequences like phantom pain.
Journal ArticleDOI
Remodelling of hand representation in adult cortex determined by timing of tactile stimulation
Xiaoqin Wang,Xiaoqin Wang,Michael M. Merzenich,Koichi Sameshima,Koichi Sameshima,William M. Jenkins +5 more
TL;DR: It is shown, using adult owl monkeys trained to respond to specific stimulus sequence events, that serial application of stimuli to the fingers results in changes to the neuronal response specificity and maps of the hand surfaces in the true primary somatosensory cortical field.
Journal ArticleDOI
Representation of a species-specific vocalization in the primary auditory cortex of the common marmoset: temporal and spectral characteristics
TL;DR: The results suggest that the representation of behaviorally important and spectrotemporally complex species-specific vocalizations in A1 is 1) temporally integrated and 2) spectrally distributed in nature, and that the represented is carried by spatially dispersed and synchronized cortical cell assemblies that correspond to each individual's vocalization in a specific and abstracted way.
References
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Journal ArticleDOI
Nerve conduction, tactile sensibility, and the electromyogram after suture or compression of peripheral nerve: a longitudinal study in man.
F Buchthal,V Kühl +1 more
TL;DR: The pattern of discrete electrical activity during voluntary effort and the prolonged duration of motor unit potentials indicate persistent enlargement of the reinnervated motor units by peripheral sprouting.
Journal ArticleDOI
Alterations in mechanoreceptor input to Brodmann's areas 1 and 3 of the postcentral hand area of Macaca mulatta after nerve section and regeneration.
TL;DR: Changes in the somatotopic organization and distribution of response-specific cortical columns in the postcentral gyrus of Macaca mulatta, following severance and regeneration of the sensory nerves of the hand are presented.
Journal ArticleDOI
The effects of de-nervation of a cutaneous area
TL;DR: The existence of accessory fibres complicates the study of the effects of section of the main nerve and of recovery of sensation in the area, and the results recorded are different from those shown by a completely de-nervated area.