scispace - formally typeset
Open AccessJournal ArticleDOI

Recursive partitioning for heterogeneous causal effects

Susan Athey, +1 more
- 05 Jul 2016 - 
- Vol. 113, Iss: 27, pp 7353-7360
Reads0
Chats0
TLDR
This paper provides a data-driven approach to partition the data into subpopulations that differ in the magnitude of their treatment effects, and proposes an “honest” approach to estimation, whereby one sample is used to construct the partition and another to estimate treatment effects for each subpopulation.
Abstract
In this paper we propose methods for estimating heterogeneity in causal effects in experimental and observational studies and for conducting hypothesis tests about the magnitude of differences in treatment effects across subsets of the population. We provide a data-driven approach to partition the data into subpopulations that differ in the magnitude of their treatment effects. The approach enables the construction of valid confidence intervals for treatment effects, even with many covariates relative to the sample size, and without “sparsity” assumptions. We propose an “honest” approach to estimation, whereby one sample is used to construct the partition and another to estimate treatment effects for each subpopulation. Our approach builds on regression tree methods, modified to optimize for goodness of fit in treatment effects and to account for honest estimation. Our model selection criterion anticipates that bias will be eliminated by honest estimation and also accounts for the effect of making additional splits on the variance of treatment effect estimates within each subpopulation. We address the challenge that the “ground truth” for a causal effect is not observed for any individual unit, so that standard approaches to cross-validation must be modified. Through a simulation study, we show that for our preferred method honest estimation results in nominal coverage for 90% confidence intervals, whereas coverage ranges between 74% and 84% for nonhonest approaches. Honest estimation requires estimating the model with a smaller sample size; the cost in terms of mean squared error of treatment effects for our preferred method ranges between 7–22%.

read more

Citations
More filters
Journal ArticleDOI

Emulate randomized clinical trials using heterogeneous treatment effect estimation for personalized treatments: Methodology review and benchmark

TL;DR: In this article , the authors reviewed and compared eleven recent heterogeneous treatment effect estimation methodologies, including meta-learner, representation learning models, and tree-based models, with application to Alzheimer's disease drug repurposing.
Book ChapterDOI

Comparison of Machine Learning Algorithms in Restaurant Revenue Prediction

TL;DR: The predictive power to validate the approach on a data about revenue of a large Russian restaurant chain is compared and methods for considering heterogeneity—observations weighting and estimating models on subsamples are described.
Journal ArticleDOI

How Do Local Government Finances Respond to the Opioid Epidemics? Evidence From Hydrocodone Rescheduling

TL;DR: The exposure to hydrocodone prescriptions and the rescheduling among regulated substances by the DEA is used as a source of exogenous variation and results are compared in three settings: standard difference-in-difference, and counterfactual created using nearest neighbors regression and generalized random forests.
Book ChapterDOI

Applications of Machine Learning Models in Regional and Demographic Economic Analysis: A Literature Survey

TL;DR: In this paper, Alpaydin et al. defined ML as a way to achieve artificial intelligence (AI) and states that ML, which is grounded in statistical theory, is the driving force and a requirement for AI.
Proceedings ArticleDOI

Simulation study in quantifying heterogeneous causal effects

TL;DR: This paper reports findings of a simulation study with four causal inference approaches, namely two single tree approaches (transformed outcome tree, causal tree), and two random forest versions of the former.
References
More filters
Journal ArticleDOI

Random Forests

TL;DR: Internal estimates monitor error, strength, and correlation and these are used to show the response to increasing the number of features used in the forest, and are also applicable to regression.
Journal ArticleDOI

Regression Shrinkage and Selection via the Lasso

TL;DR: A new method for estimation in linear models called the lasso, which minimizes the residual sum of squares subject to the sum of the absolute value of the coefficients being less than a constant, is proposed.
Book

The Nature of Statistical Learning Theory

TL;DR: Setting of the learning problem consistency of learning processes bounds on the rate of convergence ofLearning processes controlling the generalization ability of learning process constructing learning algorithms what is important in learning theory?

Statistical learning theory

TL;DR: Presenting a method for determining the necessary and sufficient conditions for consistency of learning process, the author covers function estimates from small data pools, applying these estimations to real-life problems, and much more.
Journal ArticleDOI

The central role of the propensity score in observational studies for causal effects

Paul R. Rosenbaum, +1 more
- 01 Apr 1983 - 
TL;DR: The authors discusses the central role of propensity scores and balancing scores in the analysis of observational studies and shows that adjustment for the scalar propensity score is sufficient to remove bias due to all observed covariates.