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Journal ArticleDOI

Reduction of Serum Cholesterol in Postmenopausal Women With Previous Myocardial Infarction and Cholesterol Malabsorption Induced by Dietary Sitostanol Ester Margarine Women and Dietary Sitostanol

Helena Gylling, +2 more
- 16 Dec 1997 - 
- Vol. 96, Iss: 12, pp 4226-4231
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TLDR
Dietary use of sitostanol ester margarine normalizes LDL cholesterol in about one third of women with previous myocardial infarction, especially in those with high baseline absorption and low synthesis of cholesterol, and in combination with statins reduces the needed drug dose.
Abstract
Background Reduction of serum cholesterol decreases mortality in primary and especially in secondary prevention. We investigated how effectively postmenopausal women with a previous myocardial infa...

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Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer

TL;DR: Many bioactive compounds are extranutritional constituents that typically occur in small quantities in foods and are grouped accordingly as phenolic compounds, including their subcategory, flavonoids as discussed by the authors.
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AHA Dietary Guidelines Revision 2000: A Statement for Healthcare Professionals From the Nutrition Committee of the American Heart Association

TL;DR: In this paper, the authors present guidelines for reducing the risk of cardiovascular disease by dietary and other lifestyle practices, which place increased emphasis on foods and an overall eating pattern and the need for all Americans to achieve and maintain a healthy body weight.
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Efficacy and Safety of Plant Stanols and Sterols in the Management of Blood Cholesterol Levels

TL;DR: Present evidence is sufficient to promote use of sterols and stanols for lowering LDL cholesterol levels in persons at increased risk for coronary heart disease.
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Plant sterols: biosynthesis, biological function and their importance to human nutrition.

TL;DR: Since the morbidity and mortality from cardiovascular disease have been dramatically reduced using cholesterol-lowering drugs (statins), the interest in plant sterols lies in their potential to act as a natural preventive dietary product.
References
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Journal ArticleDOI

Quantitative isolation and gas–liquid chromatographic analysis of total fecal bile acids

TL;DR: This experiment indicated the stability of bile acid structure during intestinal transit and provided additional evidence for the completeness of the described method of determining fecal bile acids.
Journal ArticleDOI

Reduction of serum cholesterol with sitostanol-ester margarine in a mildly hypercholesterolemic population

TL;DR: In this paper, the authors tested the tolerability and cholesterol-lowering effect of margarine containing sitostanol ester in a population with mild hypercholesterolemia.
Journal ArticleDOI

Quantitative isolation and gas--liquid chromatographic analysis of total dietary and fecal neutral steroids.

TL;DR: The sensitivity of the method is such that I-g fecal aliquots containing as little as 25 pg of mixed neutral steroids can be analyzed accurately, but the procedure lends itself well to preparative scale work for more definitive study of individual neutral steroids.
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Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population

TL;DR: The serum non-cholesterol sterols are significant indicators of cholesterol absorption and synthesis even under basal conditions and, since gas liquid chromatographic determination of these sterols is quite simple, their measurement may be valuable for monitoring cholesterol metabolism in large-scale epidemiologic studies.
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