Journal ArticleDOI
Reexamination of functional subdivisions of the rodent prefrontal cortex.
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TLDR
Selective patterns of behavioral deficits were observed on tests of spatial or olfactory learning after different cortical lesions in rats, similar in magnitude and quality to those found in monkeys after discrete ablations of frontal lobe regions that are argued to be homologous prefrontal subdivisions.About:
This article is published in Experimental Neurology.The article was published on 1983-02-01. It has received 175 citations till now. The article focuses on the topics: Prefrontal cortex & Frontal lobe.read more
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Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
Deborah C. Rice,Stan Barone +1 more
TL;DR: Of critical concern is the possibility that developmental exposure to neurotoxicants may result in an acceleration of age-related decline in function, and the fact that developmental neurotoxicity that results in small effects can have a profound societal impact when amortized across the entire population and across the life span of humans.
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Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat.
TL;DR: The anterograde tracer Phaseolus vulgaris‐leucoagglutinin was used to examine the topographical organization of the projections to the striatum arising from the various cytoarchitectonic subdivisions of the prefrontal cortex in the rat.
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Functions of the frontal cortex of the rat: A comparative review
TL;DR: There appears to be a remarkable unity in frontal cortex function across the class mammalia, and it is proposed that the principal function of the prefrontal cortex of mammals is the temporal organization of behavior.
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Organization of the afferent connections of the mediodorsal thalamic nucleus in the rat, related to the mediodorsal-prefrontal topography
TL;DR: The results of the present experiments indicate that the mediodorsal nucleus, on the basis of its cyto-, myelo- and chemoarchitecture as well as the organization of its reciprocal connections with the prefrontal cortex, can be subdivided into a medial, a central, a lateral and a paralamellar segment.
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Book
The Prefrontal Cortex: Anatomy, Physiology, and Neuropsychology of the Frontal Lobe
TL;DR: Anatomy of the prefrontal cortex chemical neurotransmission animal neuropsychological neurophysiology human neuropsychology neuroimaging overview of prefrontal functions - the temporal organization of behaviour.
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The cortical projections of the mediodorsal nucleus and adjacent thalamic nuclei in the rat
J. E. Krettek,Joseph L. Price +1 more
TL;DR: The mediodorsal nucleus of the rat thalamus has been divided into medial, central and lateral segments, and these segments have been shown by experiments using the autoradiographic method of demonstrating axonal connections to project to seven distinct cortical areas covering most of the frontal pole of the hemisphere.
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Limbic lesions and the problem of stimulus--reinforcement associations.
TL;DR: Only the impairment produced by the TPA lesion was consistent with a difficulty in the formation of such associations, an interpretation which is strengthened by a consideration of the gross behavioral abnormalities that have been described repeatedly following this same lesion.
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The prefrontal cortex of the rat. I. cortical projection of the mediodorsal nucleus. II. efferent connections
TL;DR: The rat's MD-projection cortex differs from that in the monkey in that it lacks a granular layer and appears to have no prominent direct associations with temporal and juxtahippocampal areas, suggesting that the striatum or thalamus receives a proportionally larger share of the MD projection in this animal than it does in themonkey.