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Journal ArticleDOI

Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Third Edition).

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TLDR
The ASRA consensus statements represent the collective experience of recognized experts in the field of neuraxial anesthesia and anticoagulation and are based on case reports, clinical series, pharmacology, hematology, and risk factors for surgical bleeding.
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This article is published in Regional Anesthesia and Pain Medicine.The article was published on 2010-01-01. It has received 1319 citations till now. The article focuses on the topics: Neuraxial blockade & Anesthesiology.

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Journal ArticleDOI

A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group

TL;DR: Ebb 761 was safe and appears capable of stabilizing and, in a substantial number of cases, improving the cognitive performance and the social functioning of demented patients for 6 months to 1 year.
Journal ArticleDOI

Oral anticoagulant drugs.

TL;DR: The vitamin K-antagonist drugs were reviewed in the Journal in the early 1970s and their safety has been improved for a number of indications without compromising efficacy, through the use of a lower degree of anticoagulation than formerly in North America.
Journal ArticleDOI

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

TL;DR: Apixaban is an orally bioavailable inhibitor of factor Xa with elimination pathways that include metabolism and renal excretion with no serious adverse events or discontinuations due to adverse effects.
Journal ArticleDOI

Heparin: mechanism of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety.

TL;DR: The mechanism of action of heparin, its pharmacokinetics, anticoagulant effects, and labo- ratory monitoring will be reviewed and the potential of a new class ofheparins, the low molecular weight heparins (LMWHs) will be discussed and their biophysical, pharmacokinetic, antithrombotic, and hemorrhagic properties will be compared with stan- dard hepar in.
Journal ArticleDOI

Maternal-perinatal outcome associated with the syndrome of hemolysis, elevated liver enzymes, and low platelets in severe preeclampsia-eclampsia

TL;DR: The presence of a "true" syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) in preeclampsia is associated with poor maternal-perinatal outcome.
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