Journal ArticleDOI
Responses of Midbrain raphe neurons to local temperature.
Tetsuro Hori,Y Harada +1 more
TLDR
The result is consistent with the idea that the heat-induced increase in brain serotonin turnover is mediated by an increased firing rate of midbrain raphe neurons.Abstract:
The effect of heating and cooling in the midbrain on the unit activities of midbrain raphe neurons in the rat was observed. Out of 24 raphe units studied, 14 units responded to a rise in midbrain temperature with an increased rate of firing. The remaining 10 units did not respond to temperature changes between 34 and 41 degrees C. The result is consistent with the idea that the heat-induced increase in brain serotonin turnover is mediated by an increased firing rate of midbrain raphe neurons.read more
Citations
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Journal ArticleDOI
Perioperative shivering: physiology and pharmacology.
TL;DR: The organization of the thermoregulatory system, and particularly the physiology of postanesthetic shivering, is reviewed and the pharmacology of thermoreGulation is discussed and the putative mechanisms and sites of action of various antishivering drugs are reviewed.
Journal ArticleDOI
Temperature receptors in the central nervous system
Jack A. Boulant,Jay B. Dean +1 more
TL;DR: The evidence for central thermosensitivity comes from thermoregulatory studies during thermal stimulation of discrete neural areas and from electrophysiological studies of temperature-sensitive neurons.
Journal ArticleDOI
Identification of an immune-responsive mesolimbocortical serotonergic system: Potential role in regulation of emotional behavior
Christopher A. Lowry,Jacob Harvey Hollis,A. de Vries,B. Pan,Laura Rosa Brunet,Jon R. F. Hunt,Julian F. R. Paton,E. van Kampen,DM Knight,Andrea Evans,Graham A. W. Rook,Stafford L. Lightman +11 more
TL;DR: The findings suggest that the immune-responsive subpopulation of serotonergic neurons in the DRI is likely to play an important role in the neural mechanisms underlying regulation of the physiological and pathophysiological responses to both acute and chronic immune activation, including regulation of mood during health and disease states.
Journal ArticleDOI
Adaptive changes in thermoregulation and their neuropharmacological basis.
K. Brück,E. Zeisberger +1 more
TL;DR: On the basis of recent insights into the organization of the thermoregulatory system, and of evaluation of experimental evidence from electrophysiological, neuropharmacological, and neuroanatomical studies it can be concluded that monoaminergic brain stem systems are involved in adaptive modifications.
Journal ArticleDOI
Integration and central processing in temperature regulation
C J Gordon,J E Heath +1 more
TL;DR: There is substantial support for the hypothesis that the afferent component of the thermoregulatory system integrates thermal stimuli into several neural patterns, the principal ones being a stepwise, switching response of neuron activity during scrotal thermal stimulation and a proportional response to other thermal inputs.
References
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Journal ArticleDOI
Ascending Monoamine Neurons to the Telencephalon and Diencephalon
TL;DR: A number of ascending monoamine neuron systems from the lower brain stem are demonstrated and mapped out by studying the anterograde and retrograde changes that occur in these neurons after various types of brain lesions.
Journal ArticleDOI
Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe
TL;DR: An inhibition of neurons containing serotonin after administration of d-lysergic acid diethylamide could account for the decreased metabolism of serotonin produced by this drug.
Journal ArticleDOI
The effect of spinal and skin temperatures on the firing rate and thermosensitivity of preoptic neurones
J. A. Boulant,J. D. Hardy +1 more
TL;DR: In anaesthetized rabbits, pre optic single unit activity was recorded while preoptic, spinal cord and skin temperatures were independently manipulated.
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