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Resting brains never rest: computational insights into potential cognitive architectures

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TLDR
A new theoretical framework for RSNs is proposed that can serve as a fertile ground for empirical testing and reflects the dynamical capabilities of the brain, which emphasizes the vital interplay of time and space.
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This article is published in Trends in Neurosciences.The article was published on 2013-05-01 and is currently open access. It has received 327 citations till now. The article focuses on the topics: Network dynamics & Resting state fMRI.

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How to Link Brain and Experience? Spatiotemporal Psychopathology of the Lived Body

TL;DR: The focus of the present article is on sketching a psychopathology of the body in schizophrenia and linking it to brain activity using converging data from psychopathological evidence, phenomenological contructs and neuroscientific measures to link the abnormalities of the trans- Phenomenal matrix to pre-phenomenal alterations of the brain resting state and of its spatiotemporal organization.
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Modular co-organization of functional connectivity and scale-free dynamics in the human brain.

TL;DR: It is suggested that FC and scale-free dynamics—hence, putatively, neuronal criticality as well—coemerge in a hierarchically modular structure in which the modules are characterized by dense connectivity, avalanche propagation, and shared dynamic states.
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Complexity Analysis of EEG, MEG, and fMRI in Mild Cognitive Impairment and Alzheimer's Disease: A Review.

TL;DR: The current review helps to reveal the patterns of dysfunction in the brains of patients with AD and to investigate whether signal complexity can be used as a biomarker to accurately respond to the functional lesion in AD.
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The brain's code and its canonical computational motifs. From sensory cortex to the default mode network: A multi-scale model of brain function in health and disease

TL;DR: The canonical model of brain function is employed to unify seemingly disparate evidence on the pathophysiology of schizophrenia in a single explanatory framework and elucidate how canonical computational motifs can be repeated across spatial and temporal scales to build a multiplexing information system able to encode and transmit information of increasing complexity.
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Temporal Dynamics of the Default Mode Network Characterize Meditation-Induced Alterations in Consciousness.

TL;DR: It is found that the alteration in the duration of the DMN microstate when meditators entered the meditative state correlated negatively with their years of meditation experience, reflecting a trait effect of meditation, highlighting its role in producing durable changes in temporal dynamics of theDMN.
References
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Journal ArticleDOI

A default mode of brain function.

TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.

TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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Functional connectivity in the resting brain: A network analysis of the default mode hypothesis

TL;DR: This study constitutes, to the knowledge, the first resting-state connectivity analysis of the default mode and provides the most compelling evidence to date for the existence of a cohesive default mode network.
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Consistent resting-state networks across healthy subjects

TL;DR: Findings show that the baseline activity of the brain is consistent across subjects exhibiting significant temporal dynamics, with percentage BOLD signal change comparable with the signal changes found in task-related experiments.
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Mapping the Structural Core of Human Cerebral Cortex

TL;DR: The spatial and topological centrality of the core within cortex suggests an important role in functional integration and a substantial correspondence between structural connectivity and resting-state functional connectivity measured in the same participants.
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