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Open AccessJournal ArticleDOI

Retinal Imaging and Image Analysis

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TLDR
Methods for 2-D fundus imaging and techniques for 3-D optical coherence tomography (OCT) imaging are reviewed and aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships.
Abstract
Many important eye diseases as well as systemic diseases manifest themselves in the retina. While a number of other anatomical structures contribute to the process of vision, this review focuses on retinal imaging and image analysis. Following a brief overview of the most prevalent causes of blindness in the industrialized world that includes age-related macular degeneration, diabetic retinopathy, and glaucoma, the review is devoted to retinal imaging and image analysis methods and their clinical implications. Methods for 2-D fundus imaging and techniques for 3-D optical coherence tomography (OCT) imaging are reviewed. Special attention is given to quantitative techniques for analysis of fundus photographs with a focus on clinically relevant assessment of retinal vasculature, identification of retinal lesions, assessment of optic nerve head (ONH) shape, building retinal atlases, and to automated methods for population screening for retinal diseases. A separate section is devoted to 3-D analysis of OCT images, describing methods for segmentation and analysis of retinal layers, retinal vasculature, and 2-D/3-D detection of symptomatic exudate-associated derangements, as well as to OCT-based analysis of ONH morphology and shape. Throughout the paper, aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships.

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Citations
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Journal ArticleDOI

Statistical atlas-based descriptor for an early detection of optic disc abnormalities.

TL;DR: It is shown that the ASD is able to characterize healthy and glaucomatous OD regions, and the deviation map extracted from the atlas can be used to assist clinicians in an early detection of deformation abnormalities in the OD region.
Patent

Method and apparatus for tomography imaging

TL;DR: In this article, a method and apparatus for determining the position of a feature of an object under test in a tomography image are disclosed, which includes: determining characterizing points, in an additional image, of the feature of interest; determining position data relating to the feature in the additional image based on the detected characterising points.
Proceedings Article

Vessel Delineation in Retinal Images using Leung-Malik filters and Two Levels Hierarchical Learning.

TL;DR: A novel supervised method to evaluate performance of Leung-Malik filters in delineating vessels and a two level hierarchical learning framework is proposed to segment vessels in retinal images with confounding disease abnormalities.
Posted Content

Reproducibility of Retinal Thickness Measurements across Spectral-Domain Optical Coherence Tomography Devices using Iowa Reference Algorithm

TL;DR: Combination of the Iowa Reference Algorithm with scanner-specific bias correction yields cross-scanner consistency of total retinal thickness measurements, facilitating scanning-device independent quantitative assessment of total Retinal thickness, longitudinal follow-up quantification without requiring patients to be imaged on the same scanner model, and allowing for multi-center studies with heterogeneous device utilization.
Book ChapterDOI

Pattern Classes in Retinal Fundus Images Based on Function Norms

TL;DR: The aim is to explain how norms in function spaces can be used to set up, automatically, classes of different retinal fundus images, and how these classifications rely on crucial and unique retinal features, such as the vascular network, whose location and measurement are appropriately quantified by weighted norms infunction spaces.
References
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Journal ArticleDOI

Distinctive Image Features from Scale-Invariant Keypoints

TL;DR: This paper presents a method for extracting distinctive invariant features from images that can be used to perform reliable matching between different views of an object or scene and can robustly identify objects among clutter and occlusion while achieving near real-time performance.

Distinctive Image Features from Scale-Invariant Keypoints

TL;DR: The Scale-Invariant Feature Transform (or SIFT) algorithm is a highly robust method to extract and consequently match distinctive invariant features from images that can then be used to reliably match objects in diering images.
Journal ArticleDOI

Optical coherence tomography

TL;DR: OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Journal ArticleDOI

A taxonomy and evaluation of dense two-frame stereo correspondence algorithms

TL;DR: This paper has designed a stand-alone, flexible C++ implementation that enables the evaluation of individual components and that can easily be extended to include new algorithms.
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