Journal ArticleDOI
Scientific and Medical Aspects of Ozone Therapy. State of the Art
TLDR
It is hoped that this report will open a dialogue among clinical scientists and will inform physicians about the beneficial effects of ozone therapy and clarify the biochemical and pharmacological mechanisms of action of ozone dissolved in biological fluids.About:
This article is published in Archives of Medical Research.The article was published on 2006-05-01. It has received 499 citations till now. The article focuses on the topics: Ozone therapy.read more
Citations
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Journal ArticleDOI
The ozone paradox: ozone is a strong oxidant as well as a medical drug.
TL;DR: In spite of a common prejudice, single ozone doses can be therapeutically used in selected human diseases without any toxicity or side effects.
Book
OZONE A New Medical Drug
TL;DR: Eventually, you will utterly discover a other experience and carrying out by spending more cash, which will guide you to understand even more going on for the globe, experience, some places, later than history, amusement, and a lot more.
Journal ArticleDOI
Mechanisms of Action Involved in Ozone Therapy: Is Healing Induced via a Mild Oxidative Stress?
Masaru Sagai,Velio Bocci +1 more
TL;DR: The versatility of ozone in treating vascular and degenerative diseases as well as skin lesions, hernial disc and primary root carious lesions in children is emphasized and the mechanisms of action of ozone therapy involve nuclear transcription factors, such as Nrf2, NFAT, AP-1, and HIF-1α are warranted.
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Efficacy of gasiform ozone and photodynamic therapy on a multispecies oral biofilm in vitro.
TL;DR: Under the conditions of the current study, gasiform ozone and PDT had a minimal effect on the viability of microorganisms organized in a cariogenic biofilm.
Journal ArticleDOI
Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility
TL;DR: A comprehensive review of O3 therapy, investigating its contraindications, routes and concentrations of administration, mechanisms of action, disinfectant properties in various microorganisms, and its medicinal use in different pathologies finds its therapeutic value in pathologies of the cardiovascular system, gastrointestinal tract, genitourinary system, central nervous system, and peripheral vascular disease.
References
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Journal ArticleDOI
Function and activation of NF-kappa B in the immune system.
TL;DR: The inhibition of NF-kappa B activation by antioxidants and specific protease inhibitors may provide a pharmacological basis for interfering with these acute processes in suppressing toxic/septic shock, graft-vs-host reactions, acute inflammatory reactions, severe phase response, and radiation damage.
Journal ArticleDOI
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
TL;DR: The results suggest that binding and/or phagocytosis of apoptotic cells induces active antiinflammatory or suppressive properties in human macrophages, likely that resolution of inflammation depends not only on the removal of apoptosis but on active suppression of inflammatory mediator production.
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Pegaptanib for Neovascular Age-Related Macular Degeneration
TL;DR: Pegaptanib, an anti-vascular endothelial growth factor therapy, was evaluated in the treatment of neovascular age-related macular degeneration.
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A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults.
Michael N. Oxman,Michael N. Oxman,Myron J. Levin,Gary R. Johnson,Kenneth E. Schmader,Sharon E. Straus,Lawrence D. Gelb,Robert D. Arbeit,Michael S. Simberkoff,Anne A. Gershon,Larry E. Davis,Adriana Weinberg,Kathy D. Boardman,Heather M. Williams,J. Hongyuan Zhang,Peter Peduzzi,C. E. Beisel,Vicki A. Morrison,John C. Guatelli,P. A. Brooks,C. A. Kauffman,Constance T. Pachucki,Kathleen M. Neuzil,Robert F. Betts,Peter F. Wright,Marie R. Griffin,P. Brunell,N. E. Soto,Adriana Marques,Susan Keay,R. P. Goodman,D. J. Cotton,John W. Gnann,J. Loutit,Mark Holodniy,Wendy A. Keitel,George E. Crawford,S. S. Yeh,Z. Lobo,John F. Toney,Richard N. Greenberg,Paul M. Keller,Ruth Harbecke,Anthony R. Hayward,Michael R. Irwin,Tassos C. Kyriakides,Christina Y. Chan,Ivan S. F. Chan,William Wang,Paula W. Annunziato,Jeffrey L. Silber +50 more
TL;DR: The zoster vaccine markedly reduced morbidity from herpes zoster and postherpetic neuralgia among older adults and significantly reduced the burden of illness due to herpesZoster.
Journal ArticleDOI
Hydrogen peroxide in the human body.
TL;DR: Urinary H2O2 levels are influenced by diet, but under certain conditions might be a valuable biomarker of ‘oxidative stress’.