Sensitivity and specificity of intracoronary injection of acetylcholine for the induction of coronary artery spasm.
Ken Okumura,Hirofumi Yasue,Koshi Matsuyama,Kazuo Goto,Hiroo Miyag,Hisao Ogawa,Kozaburo Matsuyama +6 more
TLDR
Intracoronary injection of acetylcholine is sensitive and reliable for the induction of coronary spasm in patients with variant angina.About:
This article is published in Journal of the American College of Cardiology.The article was published on 1988-10-01 and is currently open access. It has received 269 citations till now. The article focuses on the topics: Coronary artery disease & Angina.read more
Citations
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Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction.
Satoshi Kurisu,Hikaru Sato,Takuji Kawagoe,Masaharu Ishihara,Yuji Shimatani,Kenji Nishioka,Yasuyuki Kono,Takashi Umemura,Suji Nakamura +8 more
TL;DR: Although the precise cause remains unclear, simultaneous multivessel coronary spasm at the epicardial artery or microvascular levels may contribute to the onset of tako-tsubo-like left ventricular dysfunction.
Journal ArticleDOI
International standardization of diagnostic criteria for microvascular angina.
Peter Ong,Paolo G. Camici,John F. Beltrame,Filippo Crea,Hiroaki Shimokawa,Udo Sechtem,Juan Carlos Kaski,C. Noel Bairey Merz +7 more
TL;DR: Standardization of diagnostic criteria for ischemic symptoms due to coronary microvascular dysfunction (CMD) is needed for further investigation of patients presenting with anginal chest pain consistent with "microvascular angina" (MVA).
Journal ArticleDOI
Stratified Medical Therapy Using Invasive Coronary Function Testing in Angina: The CorMicA Trial
Thomas J. Ford,Bethany Stanley,Richard Good,Paul Rocchiccioli,Margaret McEntegart,Stuart Watkins,Hany Eteiba,Aadil Shaukat,Mitchell Lindsay,Keith Robertson,Stuart Hood,Ross McGeoch,Robert McDade,Eric Yii,Novalia Sidik,Peter McCartney,David Corcoran,Damien Collison,Christopher Rush,Alex McConnachie,Rhian M. Touyz,Keith G. Oldroyd,Colin Berry +22 more
TL;DR: Stratifiedmedical therapy, including an IDP with linked medical therapy, is routinely feasible and improves angina in patients with no obstructive CAD, according to a randomized, controlled, blinded clinical trial.
Journal ArticleDOI
International standardization of diagnostic criteria for vasospastic angina
John F. Beltrame,Filippo Crea,Juan Carlos Kaski,Hisao Ogawa,Peter Ong,Udo Sechtem,Hiroaki Shimokawa,C. Noel Bairey Merz +7 more
TL;DR: The Coronary Vasomotion Disorders International Study Group (COVADIS) was established to develop international standards for the diagnostic criteria of coronary vasomotor disorders, which included the criteria for vasospastic angina.
Journal ArticleDOI
An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group.
Vijay Kunadian,Alaide Chieffo,Paolo G. Camici,Colin Berry,Javier Escaned,Angela H.E.M. Maas,Eva Prescott,Nicole Karam,Yolande Appelman,Chiara Fraccaro,Gill Louise Buchanan,Stéphane Manzo-Silberman,Rasha Al-Lamee,Evelyn Regar,Alexandra Lansky,Alexandra Lansky,J. Dawn Abbott,Lina Badimon,Dirk J. Duncker,Roxana Mehran,Davide Capodanno,Andreas Baumbach,Andreas Baumbach +22 more
TL;DR: This consensus document provides a definition of INOCA and guidance to the community on the diagnostic approach and management of IN OCA based on existing evidence from research and best available clinical practice; noting gaps in knowledge and potential areas for further investigation.
References
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Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries
P L Ludmer,Andrew P. Selwyn,Thomas Shook,R R Wayne,Gilbert H. Mudge,Robert Alexander,Peter Ganz +6 more
TL;DR: The preliminary findings suggest that the abnormal vascular response to acetylcholine may represent a defect in endothelial vasodilator function, and may be important in the pathogenesis of coronary vasospasm.
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“Variant” angina: One aspect of a continuous spectrum of vasospastic myocardial ischemia: Pathogenetic Mechanisms, Estimated Incidence and Clinical and Coronary Arteriographic Findings in 138 Patients
Attilio Maseri,Silva Severi,Maurizio De Nes,Antonio L'Abbate,Sergio Chierchia,Mario Marzilli,Anna Maria Ballestra,Oberdan Parodi,Andrea Biagini,Alessandro Distante +9 more
TL;DR: Angiography in all 37 patients studied during angina revealed a severe coronary vasospasm involving vessels with extremely variable extent of atherosclerosis, which may evolve into acute myocardial infarction and sudden death.
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Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm.
Hirofumi Yasue,Yutaka Horio,Natsuki Nakamura,Hiromi Fujii,Nobuya Imoto,Ryuji Sonoda,Kiyotaka Kugiyama,Kenji Obata,Yasuhiro Morikami,Tadashi Kimura +9 more
TL;DR: It is concluded that the intracoronary injection of ACh induces coronary spasm and attack in patients with variant angina and that the activity of the parasympathetic nervous system may play a role in the pathogenesis of coronary spasms.
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Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm.
TL;DR: It is concluded that there is circadian variation of exercise capacity in patients with Prinzmetal's variant angina caused by coronary arterial spasm induced by exercise in the early morning but not in the afternoon.
Journal ArticleDOI
Coronary-artery spasm.
L. D. Hillis,Eugene Braunwald +1 more
TL;DR: Detailed formal protocol with illustrations and extensive bibliography is presented.