scispace - formally typeset
Open AccessJournal ArticleDOI

Sex Differences in Mortality from COVID-19 Pandemic: Are Men Vulnerable and Women Protected?

TLDR
This report explores plausible reasons for this sex difference in mortality from COVID-19 including the contribution of underlying cardiovascular risk factors, high risk behaviors, immune response and biological differences between men and women.
Abstract
Sex-disaggregated data are important for reducing health inequities in medicine. Global data suggest that there is a sex difference in mortality from the 2019 novel coronavirus disease. In this report, we explore plausible reasons for this sex difference, including the contribution of underlying cardiovascular risk factors, high-risk behaviors, immune response, and biological differences between men and women. (Level of Difficulty: Beginner.)

read more

Citations
More filters
Journal ArticleDOI

Barriers and facilitators of adherence to social distancing recommendations during COVID-19 among a large international sample of adults

TL;DR: It is found that adherence to social distancing recommendations vary depending on the behaviour, with none of the surveyed behaviours showing perfect adherence.
Journal ArticleDOI

Men and COVID-19: A Biopsychosocial Approach to Understanding Sex Differences in Mortality and Recommendations for Practice and Policy Interventions.

TL;DR: A stepwise approach to clinical, public health, and policy interventions are proposed to reduce COVID-19–associated morbidity and mortality among men and what health professionals and policy makers can do, and are doing, to address the unique CO VID-19-associated needs of men.
Journal ArticleDOI

Sex differences in susceptibility, severity, and outcomes of coronavirus disease 2019: Cross-sectional analysis from a diverse US metropolitan area.

TL;DR: In this article, the authors conducted a cross-sectional analysis of data from a COVID-19 Surveillance and Outcomes Registry (CURATOR) and found that males were more likely to have complications, require ICU admission and mechanical ventilation, and had higher mortality than females.
Journal ArticleDOI

Impact of the Burden of COVID-19 in Italy: Results of Disability-Adjusted Life Years (DALYs) and Productivity Loss.

TL;DR: The socio-economic burden of COVID-19 pandemic in Italy through the estimation of Disability-Adjusted Life Years (DALYs) and productivity loss was around EUR 100 million, based on data from official governmental sources collected since the inception of epidemic.
References
More filters
Journal ArticleDOI

Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

TL;DR: Hospitalised COVID-19 patients are frequently elderly subjects with co-morbidities receiving polypharmacy, all of which are known risk factors for d
Journal ArticleDOI

Sex differences in immune responses

TL;DR: It is emphasized that sex is a biological variable that should be considered in immunological studies and contribute to variations in the incidence of autoimmune diseases and malignancies, susceptibility to infectious diseases and responses to vaccines in males and females.
Journal Article

Gender differences in the utilization of health care services.

TL;DR: Women have higher medical care service utilization and higher associated charges than men, and these findings have implications for health care.
Journal ArticleDOI

The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2.

TL;DR: The first state-of-art single cell atlas of adult human heart revealed that pericytes with high expression of ACE2 might act as the target cardiac cell of SARS-CoV-2, and explains the high rate of severe cases among COVID-19 patients with basic cardiovascular disease.
Related Papers (5)