Journal ArticleDOI
Simultaneous determination of 23 amino acids and 7 biogenic amines in fermented food samples by liquid chromatography/quadrupole time-of-flight mass spectrometry.
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TLDR
A novel liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (LC-Q-TOFMS) method was developed and successfully applied to the analysis of amino acids and biogenic amines in beer, cheese and sausage samples.About:
This article is published in Journal of Chromatography A.The article was published on 2011-12-23. It has received 107 citations till now. The article focuses on the topics: Dansyl chloride & Biogenic amine.read more
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Recent analytical approaches to the analysis of biogenic amines in food samples
TL;DR: In this article, a review provides an overview on the studies published between 2011 and 2012, focusing on novelty, improvement, and optimization of analytical methods for the determination of BAs and on their applications to the important groups of food products.
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A fast, reliable, ultra high performance liquid chromatography method for the simultaneous determination of amino acids, biogenic amines and ammonium ions in cheese, using diethyl ethoxymethylenemalonate as a derivatising agent.
Begoña Redruello,Victor Ladero,Isabel Cuesta,Jorge R. Alvarez-Buylla,Maria Cruz Martin,María Dolores Lanzarote Fernández,Miguel A. Alvarez +6 more
TL;DR: Derivatisation treatment with diethyl ethoxymethylenemalonate followed by ultra-HPLC allowed the simultaneous quantification of 22 amino acids, 7 biogenic amines and ammonium ions in cheese samples in under 10 min, which is the fastest elution time ever reported for such a resolution.
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Recent trends in the determination of biogenic amines in fermented beverages – A review
TL;DR: Although biogenic amines have been determined in wine and other fermented beverages for decades, new advancements and technical possibilities have allowed to increase the accuracy and sensitivity of analytical methods, in order to overcome the challenges posed by the complex matrices and their high intrinsic variability.
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Neuroactive compounds in foods: Occurrence, mechanism and potential health effects.
TL;DR: This comprehensive review is to investigate the neuroactive compounds found naturally in foods or formed during fermentation, their formation pathways in humans, plants and microorganisms, potential health effects, effects of diet on the formation of microbial metabolites including neuro active compounds in the gut are discussed.
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Rapid determination of amino acids in fruits of Ziziphus jujuba by hydrophilic interaction ultra-high-performance liquid chromatography coupled with triple-quadrupole mass spectrometry.
TL;DR: This study showed that HILIC-UHPLC-TQ-MS is an effective technique to analyze underivatized amino acids in the food samples.
References
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Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS.
TL;DR: Practical, experimental approaches for studying, identifying, and eliminating the effect of matrix on the results of quantitative analyses by HPLC-MS/MS are described and it is demonstrated that, for the investigational drug under study, the matrix effect was clearly observed when ISP interface was utilized but it was absent when the HN interface was employed.
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Analytical properties of the nanoelectrospray ion source.
Matthias Wilm,Matthias Mann +1 more
TL;DR: Improved desolvation in nanoES led to instrument-limited resolution of the signals of a glycoprotein and the ability to signal average extensively allowed the C-terminal sequencing of a 40 kDa protein.
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Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications.
Thomas Th,T. J. Thomas +1 more
TL;DR: A large body of data indicates that polyamine pathway can be a molecular target for therapeutic intervention in several types cancers andhibitors of biosynthesis, polyamine analogues as well as oligonucleotide/polyamine analogue combinations are promising drug candidates for chemoprevention and/or treatment of cancer.
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Systematic and comprehensive strategy for reducing matrix effects in LC/MS/MS analyses
TL;DR: The combination of polymeric mixed-mode SPE, the appropriate mobile phase pH and UPLC technology provides significant advantages for reducing matrix effects resulting from plasma matrix components and in improving the ruggedness and sensitivity of bioanalytical methods.
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Signal suppression/enhancement in high-performance liquid chromatography tandem mass spectrometry
TL;DR: The review discusses the pitfalls of the matrix effect in mass spectrometry detection hyphenated to liquid chromatography separation and proposes hypotheses to explain the observed behaviours and proposes methods and strategies to overcome the matrix effects.