Journal ArticleDOI
Some mechanistic aspects of a nickel-catalyzed electrochemical cross-coupling between aryl halides and substituted chloropyridazines
Karène Urgin,Rachid Barhdadi,Sylvie Condon,Eric Léonel,Muriel Pipelier,Virginie Blot,Christine Thobie-Gautier,Didier Dubreuil +7 more
TLDR
In this paper, the electrochemical behavior of the divalent nickel complex is affected by the presence of pyridazine rings which act as co-ligands of nickel, and cyclic voltammetry indicates that the cross-coupling reaction involves first a rapid oxidative addition of the chloropyridine on the electrogenerated zerovalent nickel complex.About:
This article is published in Electrochimica Acta.The article was published on 2010-06-01. It has received 21 citations till now. The article focuses on the topics: Aryl halide & Aryl.read more
Citations
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Journal ArticleDOI
Electrochemical Arylation Reaction.
TL;DR: The electrochemical formation of the aryl-substrate bond is discussed for aromatic substrates, heterocycles, other multiple bond systems, and even at saturated carbon substrates.
Journal ArticleDOI
Electrocatalysis as an enabling technology for organic synthesis.
TL;DR: In this article, a review highlights key innovations within the past decade in the area of synthetic electrocatalysis, with emphasis on the mechanisms and catalyst design principles underpinning these advancements, and a host of oxidative and reductive electrocatalytic methodologies are discussed and grouped according to the classification of the synthetic transformation and the nature of the electrocatalyst.
Journal ArticleDOI
Nickel-Catalyzed Chain-Walking Cross-Electrophile Coupling of Alkyl and Aryl Halides and Olefin Hydroarylation Enabled by Electrochemical Reduction.
Gadde Sathish Kumar,Anatoly A. Peshkov,Aleksandra Brzozowska,Pavlo Nikolaienko,Chen Zhu,Magnus Rueping +5 more
TL;DR: The first electrochemical approach for the nickel-catalyzed cross-electrophile coupling was developed and provides a novel route to afford 1,1-diarylalkane derivatives from simple and readily available alkyl and aryl halides in good yields and excellent regioselectivities under mild conditions.
Journal ArticleDOI
Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers
Hui Qiu,Bin Shuai,Yun-Zhao Wang,Dong Liu,Yue-Gang Chen,Pei-Sen Gao,Hong-Xing Ma,Song Chen,Tian-Sheng Mei +8 more
TL;DR: A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided cell.
Journal ArticleDOI
A highly active Ni/ZSM-5 catalyst for complete hydrogenation of polymethylbenzenes
TL;DR: In this paper, the authors reported a new strategy for in situ preparation of highly active SNCs by decomposing NTC at 100 8C to highly dispersive Ni onto ZSM-5.
References
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Journal ArticleDOI
Theory of Stationary Electrode Polarography. Single Scan and Cyclic Methods Applied to Reversible, Irreversible, and Kinetic Systems.
R. S. Nicholson,Irving. Shain +1 more
TL;DR: In this paper, the integral equations obtained from the boundary value problems were solved and extensive data were calculated which permit construction of stationary electrode polarograms from theory, making it possible to develop diagnostic criteria so that unknown systems can be characterized by studying the variation of peak current, half-peak potential, or ratio of anodic to cathodic peak currents as a function of rate of voltage scan.
Journal ArticleDOI
Mechanism of biaryl synthesis with nickel complexes
T. T. Tsou,Jay K. Kochi +1 more
Journal ArticleDOI
Synthesis, Cytotoxicity, and Antitumor Activity of Copper(II) and Iron(II) Complexes of 4N-Azabicyclo[3.2.2]nonane Thiosemicarbazones Derived from Acyl Diazines
Johnny Easmon,Gerhard Pürstinger,Gottfried Heinisch,Thomas Roth,Heinz H. Fiebig,Wolfgang Holzer,Walter Jäger,Marcel Jenny,Johann Hofmann +8 more
TL;DR: Interestingly, compounds 5, 5Cu(II), and 8 were found to be potent inducers of apoptosis in Burkitt's lymphoma cells, and these compounds are also noncell cycle specific agents.