Journal ArticleDOI
Structure and function of the brain serotonin system.
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This article is published in Physiological Reviews.The article was published on 1992-01-01. It has received 2457 citations till now. The article focuses on the topics: Serotonergic & Serotonin.read more
Citations
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Spinal and Supraspinal Factors in Human Muscle Fatigue
TL;DR: Evidence for "central" fatigue and the neural mechanisms underlying it are reviewed, together with its terminology and the methods used to reveal it.
Journal ArticleDOI
Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop
André Parent,Lili-Naz Hazrati +1 more
TL;DR: The basal ganglia circuitry is designed so as to modulate in a precise manner the neuronal activity of several brain functional systems, which are involved in the direct control of different aspects of psychomotor behavior.
Journal ArticleDOI
Coevolution of neocortical size, group size and language in humans
TL;DR: It is suggested that the evolution of large groups in the human lineage depended on developing a more efficient method for time-sharing the processes of social bonding and that language uniquely fulfills this requirement.
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The developmental role of serotonin: news from mouse molecular genetics
TL;DR: New genetic models that target the serotonin system show that transient alterations in serotonin homeostasis cause permanent changes to adult behaviour and modify the fine wiring of brain connections.
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The spectrum of behaviors influenced by serotonin
TL;DR: The diverse array of behavioral effects of serotonin form the basis for understanding its potential role as an etiological marker in psychiatric disorders and for the successful pharmacologic intervention of drugs regulating serotonin neurotransmission in behavior.
References
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Journal ArticleDOI
Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry.
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Two Receptor Systems for Corticosterone in Rat Brain: Microdistribution and Differential Occupation
TL;DR: It is concluded that CORT action via CR may be involved in a tonic (permissive) influence on brain function with the septohippocampal complex as a primary target.
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Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study
TL;DR: The results suggest that the PVH plays a critical role in the modulation of ACTH and beta-endorphin release from the pituitary, and that CRF-containing pathways in the brain are involved in the mediation of autonomic responses.
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An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat
Efrain C. Azmitia,Menahem Segal +1 more
TL;DR: The differential projections from the dorsal raphe and median raphe nuclei of the midbrain were autoradiographically traced in the rat brain after 3H‐proline micro‐injections to identify six ascending fiber tracts.
Journal Article
Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol
TL;DR: It is proposed that [3H]5-HT and[3H]-spiroperidol label distinct populations of serotonin receptors in rat brain, designated 5-HT1 and 5- HT2 receptors, respectively.