Journal ArticleDOI
Structure of porcine thyrotropin releasing hormone.
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This article is published in Biochemistry.The article was published on 1970-03-01. It has received 181 citations till now. The article focuses on the topics: Thyrotropin-releasing hormone receptor & Thyrotropin-releasing hormone.read more
Citations
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Journal ArticleDOI
Hypothalamic Regulatory Hormones
TL;DR: Polypeptides isolated from hypothalamic tissue selectively stimulate or inhibit the release of anterior pituitary hormones and melanocyte-stimulating hormone.
Book
Chemoarchitecture of the brain
TL;DR: A survey of Chemically Defined Cell Groups and Pathways found new Entities in the Central Nervous System and Comment on the Functional Significance of POMC Derivatives.
Journal ArticleDOI
Brain peptides as neurotransmitters.
TL;DR: Peptides, such as cholecystokinin and vasoactive intestinal polypeptide, were known as intestinal hormones and later recognized as brain constituents and may also be central neurotransmitters.
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Peptides in the brain: the new endocrinology of the neuron.
TL;DR: After several years of pilot studies involving both biology and relatively simple chemistry in several laboratories in the USA, Europe and Japan, it became clear that characterizing these hypothalamic hypophysiotropic substances would be a challenge of (originally) unsuspected proportions.
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Depressant action of TRH, LH-RH and somatostatin on activity of central neurones.
TL;DR: It is found that TRH, LH–RH and somatostatin have a potent depressant action on the activity of neurones at several levels (cerebral and cerebellar cortex brain stem and hypothalamus) of the neural axis.
References
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Journal ArticleDOI
The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide.
TL;DR: This formulation of structure represents the elucidation of the first of the hypothalamic hormones that have been sought for so long and is chemically based on the chromatographic identity in seventeen diversified systems and biologically based on a quantitative comparison of the hormonal activities of the natural and synthetic products.
Book ChapterDOI
[52] Sequential degradation plus dansylation
TL;DR: This chapter describes the procedure and applicability of the sequential degradation plus dansylation method, used extensively in several investigations of the amino acid sequences of proteins, notably that of α-chymotrypsin.
Journal ArticleDOI
Human fibrinopeptides. Isolation, characterization and structure.
TL;DR: The structure of human fibrinogen and the specificity of thrombin is discussed, with a focus on the A-, AP- and Y-peptides.
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The antral hormone gastrin. structure of gastrin.
Journal ArticleDOI
Structure and pharmacological actions of eledoisin, the active endecapeptide of the posterior salivary glands of eledone
Vittorio Erspamer,A. Anastasi +1 more
TL;DR: Viene descritto il procedimento che ha permesso l'isolamento ed il chiarimento della struttura chimica dell'eledoisina, l'endecapeptide attivo delle ghiandole salivari posteriori dell's Eledone.