Surface treatment of biomaterials by ion beam processes

TLDR: A review of the major medical device applications of ion beam-based technologies can be found in this paper, where the authors discuss the use of ion implantation and ion-assisted deposition (IBAD) for surface treatment of biomaterials.

Abstract: Surface treatment of biomaterials is becoming an increasingly popular method of improving device function and biocompatibility without the expense and time required to develop new materials. Ion-beam-based processes, such as ion implantation and ionbeam-assisted deposition (IBAD), have proven particularly successful in this area because they offer a wide array of beneficial surface property modifications without adversely affecting bulk properties. For instance, orthopedic prostheses are made harder and more wear resistant by ion implanting their articulating surfaces. Many other devices, such as orthodontic appliances, surgical instruments and venous catheters, are treated to improve friction, fretting resistance and biocompatibility. IBAD is used to apply antimicrobial coatings to catheters and other devices, to apply sealant coatings to prevent oxygen or water vapor permeation, and to create metallized traces on polymers for use in flexible circuitry. This paper reviews the major medical device applications of ion beam-based technologies.