Journal ArticleDOI
The Added Role of MR Imaging in Treatment Stratification of Patients with Gynecologic Malignancies: What the Radiologist Needs to Know
TLDR
The purpose of this review is to highlight the added role of MR imaging in the treatment stratification and overall care of patients with endometrial, cervical, or ovarian cancer.Abstract:
Advances in MR imaging techniques, along with the growing role of the radiologist as part of a multidisciplinary treatment-planning team, have become central in tailoring treatment options and frequently lead to modifications in the therapeutic approach in patients with gynecologic malignancies.read more
Citations
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Journal ArticleDOI
Preoperative tumor size at MRI predicts deep myometrial invasion, lymph node metastases, and patient outcome in endometrial carcinomas
Sigmund Ytre-Hauge,Jenny Hild Aase Husby,Inger Johanne Magnussen,Henrica M.J. Werner,Øyvind Salvesen,Line Bjørge,Jone Trovik,Ingunn M. Stefansson,Ingunn M. Stefansson,Helga B. Salvesen,Helga B. Salvesen,Ingfrid S. Haldorsen,Ingfrid S. Haldorsen +12 more
TL;DR: Tumor size is a strong prognostic factor in endometrial carcinomas and may potentially improve preoperative risk stratification models and thus enable better tailored surgical treatment inendometrial cancer.
Journal ArticleDOI
Standardized uptake value and apparent diffusion coefficient of endometrial cancer evaluated with integrated whole-body PET/MR: Correlation with pathological prognostic factors.
I-Lun Shih,Ruoh-Fang Yen,Chi-An Chen,Bang-Bin Chen,Shwu-Yuan Wei,Wen-Chun Chang,Bor-Ching Sheu,Wen-Fang Cheng,Yao-Hui Tseng,Xin-Jia Chen,Chi-Hau Chen,Lin-Hung Wei,Ying-Cheng Chiang,Pao-Ling Torng,Men-Luh Yen,Tiffany Ting-Fang Shih +15 more
TL;DR: To evaluate the correlation between maximum standardized uptake value (SUVmax) and minimum apparent diffusion coefficient (ADCmin) of endometrial cancer derived from an integrated positron emission tomography / magnetic resonance (PET/MR) system and to determine their correlation with pathological prognostic factors.
Journal ArticleDOI
Second-Opinion Interpretations of Gynecologic Oncologic MRI Examinations by Sub-Specialized Radiologists Influence Patient Care
Yulia Lakhman,Melvin D'Anastasi,Melvin D'Anastasi,Maura Miccò,Chiara Scelzo,Hebert Alberto Vargas,Stephanie Nougaret,Ramon E. Sosa,Dennis S. Chi,Nadeem R. Abu-Rustum,Hedvig Hricak,Evis Sala +11 more
TL;DR: If second-opinion review of gynaecologic oncologic (GynOnc) magnetic resonance imaging (MRI) by sub-specialized radiologists impacts patient care is found to be a valuable clinical service, as one-fifth of MRIs had important discrepancies between initialand second-OPinion interpretations.
Journal ArticleDOI
Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study.
Katja Pinker,Piotr Andrzejewski,Pascal A. T. Baltzer,Stephan H. Polanec,Alina Sturdza,Dietmar Georg,Thomas H. Helbich,Georgios Karanikas,Christoph Grimm,Stephan Polterauer,Richard Poetter,Wolfgang Wadsak,Markus Mitterhauser,Petra Georg +13 more
TL;DR: Fused multiparametric positron emission tomography/magnetic resonance imaging in patients with cervical cancer facilitates the acquisition of independent predictive and prognostic imaging parameters and provides information on tumor heterogeneity, which has the potential to improve the planning of CRT.
Journal ArticleDOI
From Staging to Prognostication: Achievements and Challenges of MR Imaging in the Assessment of Endometrial Cancer.
Stephanie Nougaret,Yulia Lakhman,Hebert Alberto Vargas,Pierre Emmanuel Colombo,Shinya Fujii,Caroline Reinhold,Evis Sala +6 more
TL;DR: In this article, a combination of T2-weighted imaging, diffusion weighted imaging, and dynamic contrast enhancement is used to stratify patients according to their risk of recurrence and to guide surgical management.
References
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Journal ArticleDOI
Cancer statistics, 2010
TL;DR: The American Cancer Society as mentioned in this paper estimated the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data regarding cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from National Center for Health Statistics.
National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology
DG Pfister,K. K. Ang,D Brizel +2 more
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and Recommendations
Anwar R. Padhani,Guoying Liu,Dow Mu-Koh,Thomas L. Chenevert,Harriet C. Thoeny,Taro Takahara,Andrew Dzik-Jurasz,Brian D. Ross,Marc Van Cauteren,David J. Collins,Dima A. Hammoud,Gordon J. S. Rustin,Bachir Taouli,Peter L. Choyke +13 more
TL;DR: DW-MRI should be tested as an imaging biomarker in the context of well-defined clinical trials, by adding DW-MRI to existing NCI-sponsored trials, particularly those with tissue sampling or survival indicators, and standards for measurement, analysis, and display are needed.