Journal ArticleDOI
The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch Bone Metastasis Study
Elsbeth Steenland,J.W.H. Leer,Hans C. van Houwelingen,Wendy J. Post,Wilbert B. van den Hout,Job Kievit,Hanneke C. J. M. de Haes,Hendrik Martijn,Bing Oei,Ernest Vonk,Elzbieta van der Steen-Banasik,Ruud Wiggenraad,J. Hoogenhout,C.C. Wárlám-Rodenhuis,Geertjan van Tienhoven,Rinus Wanders,J. Pomp,M. van Reijn,Thijs van Mierlo,Ewald H. J. M. Rutten +19 more
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TLDR
The global analysis of the Dutch study indicates the equality of a single fraction as compared to a 6 fraction treatment in patients with painful bone metastases provided that 4 times more retreatments are accepted in the single dose group.About:
This article is published in Radiotherapy and Oncology.The article was published on 1999-08-01. It has received 589 citations till now. The article focuses on the topics: Pain scale & Palliative care.read more
Citations
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Journal ArticleDOI
Palliative Radiotherapy Trials for Bone Metastases: A Systematic Review
TL;DR: No significant differences in the arms were observed for overall and CR rates in both intention-to-treat and assessable patients, however, a significantly higher re-treatment rate with SFs was evident.
Journal ArticleDOI
Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline.
Stephen Lutz,Lawrence Berk,Eric L. Chang,Edward Chow,Carol A. Hahn,Peter Hoskin,David R. Howell,Andre Konski,Lisa A. Kachnic,Simon S. Lo,Arjun Sahgal,Larry N. Silverman,Charles von Gunten,Ehud Mendel,Andrew D. Vassil,Deborah Watkins Bruner,William F. Hartsell +16 more
TL;DR: Radiotherapy is a successful and time efficient method by which to palliate pain and/or prevent the morbidity of bone metastases and is recommended for surgical decompression and postoperative radiotherapy in highly selected patients with sufficient performance status and life expectancy.
Journal ArticleDOI
Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study.
Matthew P. Goetz,Matthew R. Callstrom,J. William Charboneau,Michael A. Farrell,Timothy P. Mans,Timothy J. Welch,Gilbert Y. Wong,Jeff A. Sloan,Paul J. Novotny,Ivy A. Petersen,Robert A. Beres,Daniele Regge,Rodolfo Capanna,Mark B. Saker,Dietrich Grönemeyer,Athour Gevargez,Kamran Ahrar,Michael A. Choti,Thierry J. Debaere,Joseph Rubin +19 more
TL;DR: RFA of painful osteolytic metastases provides significant pain relief for cancer patients who have failed standard treatments, with a 2-unit drop considered clinically significant.
Journal ArticleDOI
Update on the systematic review of palliative radiotherapy trials for bone metastases
TL;DR: Overall and complete response rates were similar in both intention-to-treat and assessable patients, and single and multiple fraction regimens provided equal pain relief; however, significantly higher retreatment rates occurred in those receiving single fractions.
Journal ArticleDOI
Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases
TL;DR: Meta-analysis of reported randomized trials shows no significant difference in complete and overall pain relief between single and multifraction palliative RT for bone metastases.
References
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Journal ArticleDOI
The measurement of clinical pain intensity: a comparison of six methods.
TL;DR: The results indicate that, for the present sample, the scales yield similar results in terms of the number of subjects who respond correctly to them and their predictive validity, however, when considering the remaining 3 criteria, the 101‐point numerical rating scale appears to be the most practical index.
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The palliation of symptomatic osseous metastases final results of the study by the radiation therapy oncology group
TL;DR: Different dose fractionation irradiation schedules have been evaluated in a randomized Radiation Therapy Oncology Group (RTOG) study to determine their palliative effectiveness in patients with osseous metastases and the low‐dose, short‐course schedules were as effective as the high‐dose protracted programs.
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Prospective randomised trial of single and multifraction radiotherapy schedules in the treatment of painful bony metastases.
TL;DR: A prospective randomised trial comparing a single fraction of 8 Gy with 30 Gy in 10 daily fractions for the relief of metastatic bone pain was performed, and pain relief was independent of the histology of the primary tumour.
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Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases
TL;DR: A single fraction of 8 Gy was as effective as 5 Gy x4 in relieving pain from bone metastasis and the need for reirradiation and toxicity was minor.
Journal ArticleDOI
Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis
TL;DR: The conclusion is that protracted dose‐fractionation schedules are more effective than short course schedules.