The elution of 51Cr from labelled leukocytes--a new theory.
Peter M. Ronai,Peter M. Ronai +1 more
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TLDR
Electrophoretic and whole body counting studies exclude the presence of significant amounts of free 51Cr (either hexavalent or trivalent) in the 51Cr that elutes from labelled cells and supports the hypothesis that 51Cr elution results from turnover of labelled protein within the cell and loss of non-reutilisable labelled protein fragments.About:
This article is published in Blood.The article was published on 1969-03-01 and is currently open access. It has received 55 citations till now.read more
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Comparison of in vitro methods to determine drug-induced cell lethality.
TL;DR: Human lymphoma cell line was exposed in vitro to increasing concentrations of adriamycin, bleomycin, and 1,3-bis(2-chloroethyl)-1-nitrosourea for 1 hr, and CF appears as the most reliable, dose-dependent index of cell lethality.
Journal ArticleDOI
What's your age again? Determination of human neutrophil half-lives revisited.
TL;DR: The current knowledge on neutrophil half‐lives is reappraised, including their production in the bone marrow, their residency in the circulation and marginated pool, and their exit from the circulation.
Journal ArticleDOI
Metabolism of the carcinogen chromate by rat liver microsomes.
J.E. Gruber,K.W. Jennette +1 more
TL;DR: Incubation of chromate with microsomes in the presence of the enzyme cofactor NADPH, resulted in reduction of chromates, but in the absence of NADPH no reduction occurred.
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Absorption and elimination of trivalent and hexavalent chromium in humans following ingestion of a bolus dose in drinking water
TL;DR: The data suggest that nearly all the ingested Cr(VI) was reduced to Cr(III) before entering the bloodstream based on comparison to RBC and plasma chromium patterns in animals exposed to high doses of Cr( VI).
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Chromium concentrations in serum, blood clot and urine from patients following total hip arthroplasty
A. Bartolozzi,Jonathan Black +1 more
TL;DR: A study of the chromium content of blood clot, in comparison to chromium concentrations in serum and urine, could shed light on the valency question and help determine chromium valence states in corrosion products in this model.
References
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Book reviewA text-book of quantitative inorganic analysis: A. I. Vogel: (including elementary instrumental analysis). 3rd Ed. Longmans, Green, London, 1962. Pp.xxx + 1216 70s.
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The tagging of leukemic leukocytes with radioactive chromium and measurement of the in vivo cell survival.
Mary Sue McCall,Mary Sue McCall,Donald A. Sutherland,Donald A. Sutherland,Anna M. Eisentraut,Anna M. Eisentraut,Henry Lanz,Henry Lanz +7 more
TL;DR: In four instances, such in vitro tagged leukocytes were shown to circulate in vivo following autotransfusion for at least 24 hours, and although the majority of the cells were rapidly removed from the circulation, in two patients the Cr 51 activity in the leukocytic fraction was followed and small numbers of tagged Leukocytes persisted in the circulation for five days.
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The use of chromium-51 as a sensitive quantitative criterion of early radiation damage to rat thymocytes.
J. F. Scaife,P. V. Vittorio +1 more
TL;DR: The uptake of Cr61-chromate by thymocytes in suspension can be used as a sensitive quantitative criterion for the evaluation of early radiation damage to these cells, often under situations where other methods of assessing cell death such as morphological changes do not yield valid results.
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The effect of antigenic stimulation on incorporation of phosphate and methionine into proteins of isolated lymph node cells
Milton Kern,Herman N. Eisen +1 more
TL;DR: The rate of phosphate incorporation into phosphoprotein was determined in cells isolated from regional lymph nodes at varying times after antigen injection, and was enhanced on the 4th day after injection.
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The fate of cr-51 labelled ehrlich ascites tumour cells.
Paul C. Vincent,Annette Nicholls +1 more
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