Journal ArticleDOI
The lens as an osmometer and the effects of medium osmolarity on water transport, 86Rb efflux and 86Rb transport by the lens
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TLDR
Within the 238–368-mosM range of media osmolarities, the lens behaved as a “perfect osmometer” and gained water while water losses were found in lenses in incubated in hyperosmotic Tyrode's media.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1968-06-11. It has received 49 citations till now. The article focuses on the topics: Water transport & Lens Fiber.read more
Citations
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Journal ArticleDOI
The lens in diabetes.
TL;DR: The changes which occur in the human lens in diabetes include refractive changes and cataract and age-related increases in thickness, curvatures, light scattering, autofluorescence and yellowing and other mechanisms, including glycation and oxidative stress are discussed.
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Molecular basis of eye lens transparency: Osmotic pressure and X-ray analysis of α-crystallin solutions☆
TL;DR: Transparency may now be expressed as a function of a few structural parameters, the role of which is discussed, and the approach presented here may be extended to studies of the thermodynamic-structural relationships of other protein solutions.
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Protein interactions in the calf eye lens: interactions between β-crystallins are repulsive whereas in γ-crystallins they are attractive
TL;DR: In this paper, the effect of temperature on X-ray scattering and osmotic pressure in β- and γ-crystallin solutions was investigated and two types of non-specific interactions were observed.
Journal Article
Biometry of primate lenses during immersion in preservation media.
TL;DR: Culture media are more effective than simple salt solutions in maintaining lens physical integrity during short-term incubations and substantial swelling and capsular separation were observed in 10 of the 22 human lenses.
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Volume regulation in the bovine lens and cataract. The involvement of chloride channels.
TL;DR: The data suggest the long-term prophylactic use of tamoxifen may make the patient more susceptible to cataract and the lens is able to volume regulate, which is concluded that it possesses volume-activated Cl- channels.
References
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Journal ArticleDOI
Entrance of water into human red cells under an osmotic pressure gradient
Victor W. Sidel,A. K. Solomon +1 more
TL;DR: A new technique to determine the rate of water passage through the membrane of the human erythrocyte under an osmotic gradient has been developed using a rapid mixing apparatus of the Hartridge-Roughton type coupled with a light-scattering device of new design.
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Osmotic effects on the amino acid-concentrating mechanism in the rabbit lens.
TL;DR: This report indicates that the ability of the lens to concentrate two nonmetabolizable amino acids, a-aminoisobutyric acid and laminocyclopentane-1-carboxylic acid,2 is markedly influenced by osmotic changes in the lens.
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The total intracellular concentration of mammalian tissues compared with that of the extracellular fluid
E. J. Conway,J. I. McCormack +1 more
TL;DR: Robinson (1950) considers that his observations can be explained only if energy derived from respiration is used to expel water from the cells, and believes that about 150-300 m.mole of unrecognized material exist in the fibre water of skeletal muscle.
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Osmolality of brain tissue and its relation to brain bulk
W. Eugene Stern,R. V. Coxon +1 more
TL;DR: It was found that a rise or fall in plasma tonicity exceeding about 45 mosmoles/kg water was accompanied by a change of osmolality of the tissue fluids of the brain in the same direction and by a corresponding loss or gain of water.
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Osmotic properties of the erythrocyte: iii. the applicability of osmotic laws to the rate of hemolysis in hypotonic solutions of non-electrolytes
TL;DR: Osmotic hemolysis, when it goes to completion, is such a rapid process-requiring for its entire course perhaps only a few seconds-that the ordinary methods of measuring the rate are of very doubtful value.