The RIFLE and AKIN classifications for acute kidney injury: a critical and comprehensive review
José António Lopes,Sofia Jorge +1 more
TLDR
A critical and comprehensive discussion of the two classifications for AKI, focusing on the main differences, advantages and limitations is provided.Abstract:
In May 2004, a new classification, the RIFLE (Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease) classification, was proposed in order to define and stratify the severity of acute kidney injury (AKI). This system relies on changes in the serum creatinine (SCr) or glomerular filtration rates and/or urine output, and it has been largely demonstrated that the RIFLE criteria allows the identification of a significant proportion of AKI patients hospitalized in numerous settings, enables monitoring of AKI severity, and is a good predictor of patient outcome. Three years later (March 2007), the Acute Kidney Injury Network (AKIN) classification, a modified version of the RIFLE, was released in order to increase the sensitivity and specificity of AKI diagnosis. Until now, the benefit of these modifications for clinical practice has not been clearly demonstrated. Here we provide a critical and comprehensive discussion of the two classifications for AKI, focusing on the main differences, advantages and limitations.read more
Citations
More filters
Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury
Ravindra L. Mehta,John A. Kellum,Sudhir V. Shah,Bruce A. Molitoris,Claudio Ronco,David G. Warnock,Adeera Levin +6 more
TL;DR: An initiative to develop uniform standards for defining and classifying AKI and to establish a forum for multidisciplinary interaction to improve care for patients with or at risk for AKI is described.
Journal ArticleDOI
Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment
TL;DR: This Review explores issues in the use of renal replacement therapy, its timing, its intensity and its preferred modalities in patients with CSA-AKI, and discusses the prognosis in terms of patient survival and kidney recovery.
Journal ArticleDOI
Safety of bacteriophage therapy in severe Staphylococcus aureus infection
Aleksandra Petrovic Fabijan,Ruby C.Y. Lin,Josephine Ho,Susan Maddocks,Susan Maddocks,Nouri L. Ben Zakour,Jonathan R. Iredell,Jonathan R. Iredell,Westmead Bacteriophage Therapy Team +8 more
TL;DR: The data indicate that AB-SA01 administered in this way is safe in severe S. aureus infections, including infective endocarditis and septic shock, and the measurements of bacterial and phage kinetics in blood samples suggest that 12 h dosing of 109 plaque-forming units may be a rational basis for further studies.
Journal ArticleDOI
Changes in Renal Function in Patients With Atrial Fibrillation: An Analysis From the RE-LY Trial
Michael Böhm,Michael D. Ezekowitz,Michael D. Ezekowitz,Stuart J. Connolly,John W. Eikelboom,Stefan H. Hohnloser,Paul A. Reilly,Helmut Schumacher,Martina Brueckmann,Stephan H. Schirmer,Mario T. Kratz,Salim Yusuf,Hans-Christoph Diener,Ziad Hijazi,Lars Wallentin +14 more
Journal ArticleDOI
Interventions for protecting renal function in the perioperative period.
Mathew Zacharias,Mohan Mugawar,G. Peter Herbison,Robert J. Walker,Karen Hovhannisyan,Pal Sivalingam,Niamh P Conlon +6 more
TL;DR: This review aimed at determining the effectiveness of various measures advocated to protect patients' kidneys during the perioperative period showed significant heterogeneity and indicated that most interventions provided no benefit.
References
More filters
Journal ArticleDOI
KDIGO clinical practice guidelines for acute kidney injury.
TL;DR: The guidelines focused on 4 key domains: (1) AKI definition, (2) prevention and treatment of AKI, (3) contrastinduced AKI (CI-AKI) and (4) dialysis interventions for the treatment ofAKI.
Journal ArticleDOI
Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group.
TL;DR: A 2-day consensus conference on acute renal failure (ARF) in critically ill patients was organized by ADQI as discussed by the authors, where the authors sought to review the available evidence, make recommendations and delineate key questions for future studies.
Journal ArticleDOI
Acute Kidney Injury Network: Report of an Initiative to Improve Outcomes in Acute Kidney Injury
Ravindra L. Mehta,John A. Kellum,Sudhir V. Shah,Bruce A. Molitoris,Claudio Ronco,David G. Warnock,Adeera Levin +6 more
TL;DR: The Acute Kidney Injury Network (AKI Network) as discussed by the authors is a multidisciplinary collaborative network focused on AKI, which was established to improve care for patients with or at risk for AKI.
Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury
Ravindra L. Mehta,John A. Kellum,Sudhir V. Shah,Bruce A. Molitoris,Claudio Ronco,David G. Warnock,Adeera Levin +6 more
TL;DR: An initiative to develop uniform standards for defining and classifying AKI and to establish a forum for multidisciplinary interaction to improve care for patients with or at risk for AKI is described.
Journal ArticleDOI
Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury
John A. Kellum,Norbert Lameire,Peter Aspelin,Rashad S. Barsoum,Emmanuel A. Burdmann,Stuart L. Goldstein,Charles A. Herzog,Michael Joannidis,Andreas Kribben,Andrew S. Levey,Alison M. MacLeod,Ravindra L. Mehta,Patrick T. Murray,Saraladevi Naicker,Steven M. Opal,Franz Schaefer,Miet Schetz,Shigehiko Uchino +17 more
Related Papers (5)
Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury
John A. Kellum,Norbert Lameire,Peter Aspelin,Rashad S. Barsoum,Emmanuel A. Burdmann,Stuart L. Goldstein,Charles A. Herzog,Michael Joannidis,Andreas Kribben,Andrew S. Levey,Alison M. MacLeod,Ravindra L. Mehta,Patrick T. Murray,Saraladevi Naicker,Steven M. Opal,Franz Schaefer,Miet Schetz,Shigehiko Uchino +17 more