Journal ArticleDOI
The Stability of N-Ethylmaleimide and its Reaction with Sulfhydryl Groups
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This article is published in Journal of the American Chemical Society.The article was published on 1955-07-01. It has received 336 citations till now.read more
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The fate of extracellular glutathione in the rat.
TL;DR: It is concluded that the degradation occurs mainly on the luminal surface of the renal brush-border membrane and that gamma-glutamyl transpeptidase is a glutathionase acting on extracellular glutathione.
Journal ArticleDOI
Spectrophotometric Assay for Sulfhydryl Groups Using N-Ethylmaleimide
Journal ArticleDOI
Small-Molecule Modulation of Protein Homeostasis.
George M. Burslem,Craig M. Crews +1 more
TL;DR: The technologies available for the control of intracellular protein levels with small molecules are discussed and the various systems available are compared.
Journal ArticleDOI
An activatable theranostic for targeted cancer therapy and imaging
Sankarprasad Bhuniya,Sukhendu Maiti,Eun Joong Kim,Hyunseung Lee,Jonathan L. Sessler,Kwan Soo Hong,Jong Seung Kim +6 more
TL;DR: It is suggested that the present strategy, which combines within a single agent the key functions of targeting, release, imaging, and treatment, may have a role to play in cancer diagnosis and therapy.
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Disulfide-based multifunctional conjugates for targeted theranostic drug delivery.
TL;DR: It is proposed that disulfide-based cancer-targeting theranostics may have a role to play in advancing drug discovery efforts, as well as improving the understanding of cellular uptake and drug release mechanisms.