Journal ArticleDOI
The yeast pyruvate kinase gene does not contain a string of non- preferred codons: Revised nucleotide sequence
TLDR
The revised sequence demonstrates that the yeast pyruvate kinase gene does not have a cluster of non‐preferred codons, and that it therefore is not an example of the class of genes which possibly exhibit translational control by the presence of non-pre preferred codons.About:
This article is published in FEBS Letters.The article was published on 1989-04-24. It has received 32 citations till now. The article focuses on the topics: Gene & Nucleic acid sequence.read more
Citations
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Journal ArticleDOI
Synonymous codon usage in Saccharomyces cerevisiae
Paul M. Sharp,Elizabeth Cowe +1 more
Journal ArticleDOI
Ribosome‐mediated translational pause and protein domain organization
T. A. Thanaraj,Patrick Argos +1 more
TL;DR: Examination of available mutagenic data indicated that the effects of some of the reported mutations were consistent with the hypothesis that the kinetics of translation influence the folding events in the growing nascent polypeptide chain.
Journal ArticleDOI
Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate.
Eckhard Boles,Frank Schulte,T Miosga,Kerstin Freidel,E Schlüter,Friedrich K. Zimmermann,Cornelis P. Hollenberg,Jürgen J. Heinisch +7 more
TL;DR: Overexpression of the YOR347c/PYK2 gene on a multicopy vector restored growth on glucose of a yeast pyruvate kinase 1 (pyk1) mutant strain and could completely substitute for the PYK1-encoded enzymatic activity.
References
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Journal ArticleDOI
Improved Estimation of Secondary Structure in Ribonucleic Acids
Ignacio Tinoco,Philip N. Borer,Barbara Dengler,Mark D. Levin,Olke C. Uhlenbeck,Donald M. Crothers,J. Bralla +6 more
TL;DR: This method can be used for predicting and assessing possible secondary structures for recently determined RNA sequences and new experimental and theoretical results allow us to improve the method, without making it more complicated.
Journal ArticleDOI
The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing.
TL;DR: It is concluded that the M1- and M2-type isozymes of pyruvate kinase are produced from the same gene probably by alternative RNA splicing.
Journal ArticleDOI
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding
TL;DR: A general method for systematically replacing amino acids in an enzyme is described, which allows analysis of their molecular roles in substrate binding or catalysis and could eventually lead to the engineering of new enzymatic activities.
Journal ArticleDOI
The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters.
TL;DR: It is concluded that the L- and R-type isozymes of pyruvate kinase are produced from a single gene by use of different promoters.