Journal ArticleDOI
Thermal analysis of sarcoplasmic reticulum membranes.
TLDR
A broad endothermic transition was detected in freeze-dried rabbit sarcoplasmic reticulum membranes which is attributable to membrane lipids and is proposed that the activity of the Ca2+ transport ATPase is limited by the local viscosity of the membrane below the transition temperature.About:
This article is published in FEBS Letters.The article was published on 1974-10-15. It has received 40 citations till now. The article focuses on the topics: Endoplasmic reticulum & Membrane.read more
Citations
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Journal ArticleDOI
Lipid phase transitions and phase diagrams. I. Lipid phase transitions.
Journal ArticleDOI
Functional interactions of lipids and proteins in rat intestinal microvillus membranes.
TL;DR: Interactions of lipids and proteins in isolated rat intestinal microvillus membranes were examined by studying the temperature dependence of enzyme activities and of D-glucose transport in relation to the membrane lipid thermotropic transition observed by fluorescence polarization and differential scanning calorimetry.
Journal ArticleDOI
Plant lipids and their role in membrane function.
Peter J. Quinn,W.P. Williams +1 more
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Cholesterol modulates activity of calcium-dependent ATPase of the sarcoplasmic reticulum.
TL;DR: The use of cholesterol-enriched liposomes to reversibly vary the content of cholesterol in the sarcoplasmic membranes is reported here and it is shown that as the cholesterol content of the membrane varies so does the activity of the Ca2+-ATPase.
References
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Journal ArticleDOI
A simple method for the isolation and purification of total lipides from animal tissues.
TL;DR: In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.
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Studies on lecithin-cholesterol-water interactions by differential scanning calorimetry and X-ray diffraction
TL;DR: The cholesterol controls the fluidity of the hydrocarbon chains of the phospholipid by disruption of the crystalline chain lattice of the gel phase, and by inhibiting the flexing of chains in the dispersed liquid crystalline phase.
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Sarcoplasmic Reticulum III. THE ROLE OF PHOSPHOLIPIDS IN THE ADENOSINE TRIPHOSPHATASE ACTIVITY AND Ca++ TRANSPORT
TL;DR: Treatment of skeletal muscle microsomes with phospholipase C inhibits the adenosine triphosphatase activity and calcium transport, parallel with the selective hydrolysis of membrane lecithin, and is accompanied by tight binding ofospholipids to the microsomal membrane.
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Temperature-induced transitions of function and structure in sarcoplasmic reticulum membranes
TL;DR: The results are consistent with an order-disorder transition involving the lipid alkyl chains of the Sarcoplasmic membrane, and with a model in which molecular motion, Ca 2+ transport and enzyme activity are limited by local viscosity of hydrophobic regions at temperatures below the transition.