Journal ArticleDOI
Total synthesis of Hirtellanine A
Shuyan Zheng,Zhengwu Shen +1 more
TLDR
The first total synthesis of hirtellanines A was described in this paper, where the key transformations include base-mediated regioselective pyran ring formation, one-pot sequential boronation and Suzuki-Miyaura cross-coupling.About:
This article is published in Tetrahedron Letters.The article was published on 2010-05-26. It has received 23 citations till now. The article focuses on the topics: Ring (chemistry) & Pyran.read more
Citations
More filters
Journal ArticleDOI
Recent applications of the Suzuki reaction in total synthesis
Majid M. Heravi,Elaheh Hashemi +1 more
Journal ArticleDOI
Multifunctional tacrine-flavonoid hybrids with cholinergic, β-amyloid-reducing, and metal chelating properties for the treatment of Alzheimer's disease.
Su-Yi Li,Xiao-Bing Wang,Sai-Sai Xie,Neng Jiang,Kelvin D.G. Wang,Hequan Yao,Hongbin Sun,Ling-Yi Kong +7 more
TL;DR: A new series of tacrine-flavonoid hybrids (13a-u) had been designed, synthesized, and evaluated as multifunctional cholinesterase (ChE) inhibitors against Alzheimer's disease (AD).
Journal ArticleDOI
Application of the Suzuki-Miyaura Reaction in the Synthesis of Flavonoids
TL;DR: The application of the Suzuki-Miyaura reaction in the synthesis of flavonoids, an important class of natural products, is reviewed and classes of flavons, including chalcones, flavones, isoflavone, neoflavones, biflavones and derivatives of Flavonoids obtained by C-C bond formation via the Suzuki
Journal ArticleDOI
Palladium-catalyzed oxidative arylation of chromones via a double C–H activation: an expedient approach to flavones
TL;DR: In this article, a palladium-catalyzed oxidative arylation of chromones was examined and a regioselective 2-arylation was carried out via a double C-H activation process.
Journal ArticleDOI
Total synthesis of the pyranoisoflavone kraussianone 1 and related isoflavones.
TL;DR: The first total synthesis of the pyranoisoflavone kraussianone 1 (1) is described, which provided access to the related isoflavones eriosemaone D (2) and genistein (3) via simple structural modifications.
References
More filters
Journal ArticleDOI
Pt(IV)-catalyzed cyclization of arene–alkyne substrates via C–H bond functionalization
TL;DR: PtCl 4 is compatible with both terminal and disubstituted alkynes, as well as with various functionalities on the arene ring, including methyl, methoxyl, hydroxyl, protected amine, and halide.
Journal ArticleDOI
Oligoresorcinols Fold into Double Helices in Water
TL;DR: It is reported that the first double helices with a controlled helicity in water based on oligoresorcinols as a new, simplest water-soluble structural motif is reported.
Journal ArticleDOI
Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo.
Andrew V. Stachulski,Neil G. Berry,A. C. Lilian Low,Shelley L. Moores,Eleanor C. Row,David C. Warhurst,I.S. Adagu,Jean-Francois Rossignol +7 more
TL;DR: In this article, the preparation and antiparasitic activity in vitro and in vivo of a series of isoflavone derivatives related to genistein was reported. But none of the derived derivatives retain the 5,7-dihydroxyisof-lavone core of the compound.
Journal ArticleDOI
Palladium-Catalyzed Borylation of Phenyl Bromides and Application in One-Pot Suzuki−Miyaura Biphenyl Synthesis
TL;DR: The coupling reaction of pinacolborane with various aryl bromides in the presence of a catalytic amount of Pd(OAc)(2) together with DPEphos as ligand and Et(3)N as base provided arieslboronates, allowing the one-pot, two-step synthesis of unsymmetrical biaryls in high yields.
Journal ArticleDOI
Total synthesis of lamellarins D, L, and N
Naotaka Fujikawa,Takeshi Ohta,Tomohiro Yamaguchi,Tsutomu Fukuda,Fumito Ishibashi,Masatomo Iwao +5 more
TL;DR: In this paper, the authors used Hinsberg-type pyrrole synthesis and palladium-catalyzed Suzuki-Miyaura coupling of the 3,4-dihydroxypyrrole bistriflate 6 as the key reactions.