Transmission dynamics of Chlamydia trachomatis affect the impact of screening programmes.
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This study shows that a longer duration of the asymptomatic period results in a more pronounced impact of a screening programme, however, due to the slower turnover of the infection, a substantial reduction in prevalence can only be achieved after screening for several years or decades.About:
This article is published in Epidemics.The article was published on 2010-09-01 and is currently open access. It has received 88 citations till now. The article focuses on the topics: Chlamydia trachomatis & Population.read more
Citations
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Sexually transmitted infections: challenges ahead
Magnus Unemo,Catriona S. Bradshaw,Jane S Hocking,Henry J. C. de Vries,Suzanna C. Francis,David Mabey,Jeanne M. Marrazzo,Gerard J.B. Sonder,Jane R. Schwebke,Elske Hoornenborg,Rosanna W. Peeling,Susan S. Philip,Nicola Low,Christopher K Fairley +13 more
TL;DR: Overall, this Commission aims to enhance the understanding of some of the key challenges facing the field of STI treatment and control, and outlines new approaches to improve the clinical management of STIs and public health.
Journal ArticleDOI
The natural history of Chlamydia trachomatis infection in women: a multi-parameter evidence synthesis
Malcolm J Price,A E Ades,Kate Soldan,Nicky J Welton,John Macleod,Ian Simms,Daniela DeAngelis,Daniela DeAngelis,Katherine Mary Elizabeth Turner,Patrick J Horner +9 more
TL;DR: The study provides new insights into the reproductive risks of PID and the role of CT, and establishes a set of interpretations of the major studies and study designs, under which a coherent set of estimates can be generated.
Journal ArticleDOI
Risk of Pelvic Inflammatory Disease Following Chlamydia trachomatis Infection: Analysis of Prospective Studies With a Multistate Model
Malcolm J Price,A E Ades,Daniela De Angelis,Nicky J Welton,John Macleod,Kate Soldan,Ian Simms,Katherine Mary Elizabeth Turner,Patrick J Horner +8 more
TL;DR: This study reappraised evidence from randomized controlled trials of screening and controlled observational studies that followed untreated CT-infected and -uninfected women to measure the development of PID and investigated the possibility that the rate of PID due to CT is greater during the period immediately following infection.
Journal ArticleDOI
Effectiveness and cost-effectiveness of traditional and new partner notification technologies for curable sexually transmitted infections: observational study, systematic reviews and mathematical modelling
Christian L. Althaus,Katherine Mary Elizabeth Turner,Catherine H Mercer,Peter Auguste,Tracy E Roberts,Gill Bell,Sereina A. Herzog,Jackie Cassell,W. John Edmunds,Peter J White,Helen Ward,Nicola Low +11 more
TL;DR: There is evidence to support the improved clinical effectiveness of EPT in reducing index case reinfection and standardised parameter sets for curable STIs should be developed for mathematical models of STI transmission that are used for policy-making.
Journal ArticleDOI
Screening for genital chlamydia infection
Nicola Low,Shelagh Redmond,Anneli Uusküla,Jan E. A. M. van Bergen,Helen Ward,Berit Andersen,Hannelore M Götz +6 more
TL;DR: The risk of PID was lower in women in intervention than control groups, with little evidence of between-trial heterogeneity, and the effect of multiple rounds of chlamydia screening on C. trachomatis transmission was compatible with no effect and was lower than in two RCTs at high or unclear risk of detection bias.
References
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Numerical Recipes in C: The Art of Scientific Computing
TL;DR: Numerical Recipes: The Art of Scientific Computing as discussed by the authors is a complete text and reference book on scientific computing with over 100 new routines (now well over 300 in all), plus upgraded versions of many of the original routines, with many new topics presented at the same accessible level.
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Infectious Diseases of Humans: Dynamics and Control
Roy M. Anderson,Robert M. May +1 more
TL;DR: This book discusses the biology of host-microparasite associations, dynamics of acquired immunity heterogeneity within the human community indirectly transmitted helminths, and the ecology and genetics of hosts and parasites.
Journal ArticleDOI
Sexually transmitted diseases treatment guidelines.
TL;DR: The new STD treatment guidelines for gonorrhea, chlamydia, bacterial vaginosis, trichomonas, vulvovaginal candidiasis, pelvic inflammatory disease, genital warts, herpes simplex virus infection, syphilis, and scabies are reviewed.
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Modeling Infectious Diseases in Humans and Animals
TL;DR: Mathematical modeling of infectious dis-eases has progressed dramatically over the past 3 decades and continues to be a valuable tool at the nexus of mathematics, epidemiol-ogy, and infectious diseases research.
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