Ultrasound-assisted one-pot, three-component synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones.
TLDR
Triethylamine was found to be an efficient catalyst for the synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by one-pot reaction of phthalhydrazide, aromatic aldehydes, and malononitrile or ethyl cyanoacetate in ethanol under ultrasonic irradiation.About:
This article is published in Ultrasonics Sonochemistry.The article was published on 2010-01-01 and is currently open access. It has received 137 citations till now. The article focuses on the topics: Malononitrile & Triethylamine.read more
Citations
More filters
Journal ArticleDOI
Fe3O4@silica sulfuric acid nanoparticles: An efficient reusable nanomagnetic catalyst as potent solid acid for one-pot solvent-free synthesis of indazolo[2,1-b]phthalazine-triones and pyrazolo[1,2-b]phthalazine-diones
Ali Reza Kiasat,Jamal Davarpanah +1 more
TL;DR: In this paper, the preparation of sulfuric acid functionalized silica-coated magnetite nanoparticles with core-shell structure was presented by using Fe 3 O 4 spheres as the core and silica sulfic acid nanoparticles as the shell, and the ability of this nanomagnetic solid acid catalyst in the one-pot three-components condensation reaction of phthalhydrazide, aromatic aldehydes and cyclic or acyclic 1,3-diketones are also described.
Journal ArticleDOI
Progress of the synthesis of condensed pyrazole derivatives (from 2010 to mid-2013).
Meng Li,Bao-Xiang Zhao +1 more
TL;DR: This review has summarized the reported synthesis methods of condensed pyrazole derivatives from 2010 until now and offers an orientation for the design and synthesis of condensed Pyrozole derivatives with good biological activities.
Journal ArticleDOI
Update 1 of: Ionic liquids in heterocyclic synthesis.
Marcos A. P. Martins,Clarissa P. Frizzo,Aniele Z. Tier,Dayse N. Moreira,Nilo Zanatta,Helio G. Bonacorso +5 more
Journal ArticleDOI
A highly efficient green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives and their photophysical studies
TL;DR: In this article, a task-specific ionic liquid, [Bmim]OH, has been used for an efficient synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by one-pot cyclocondensation reaction of phthalhydrazide, aromatic aldehydes, and malononitrile or ethyl cyanoacetate under microwave irradiation.
Journal ArticleDOI
Ultrasound-Assisted Synthesis of Pyrazolo[3,4-b]pyridines as Potential Corrosion Inhibitors for Mild Steel in 1.0 M HCl
TL;DR: In this article, five pyrazolopyridine derivatives were synthesized using ultrasonic irradiation in aqueous medium using p-TSA as a catalyst, and their effect on corrosion of mild steel (MS) in 1.0 M HCl has been investigated using different experimental techniques like weight loss, electrochemical impedance spectroscopy (EIS), and potentiodynamic polarization techniques.
References
More filters
Journal ArticleDOI
Recent developments in isocyanide based multicomponent reactions in applied chemistry
Journal ArticleDOI
Multicomponent Reactions with Isocyanides.
Alexander Dömling,Ivar Ugi +1 more
TL;DR: MCRs and especially MCRs with isocyanides offer many opportunities to attain new reactions and basic structures, however, this requires that the chemist learns the "language" of M CRs, something that this review wishes to stimulate.
Journal ArticleDOI
Multicomponent reactions in organic-chemistry
TL;DR: In this paper, it has been shown that effective syntheses can be carried out using three, or sometimes more, reactants simultaneously and a few such processes are used industrially.
Journal ArticleDOI
Unsaturated O- and N-heterocycles from carbohydrate feedstocks.
TL;DR: A broad structural variety of products emerges that have not only diverse chemical functionalities but also hydrophilic "residual sugar" portions that render them water-soluble and readily biodegradable.
Journal ArticleDOI
Identification of antitumor activity of pyrazole oxime ethers.
TL;DR: 5-phenoxypyrazole was comparable to doxorubicin, while exhibiting very potent cytotoxicity against XF 498 and HCT15, and pyrazole oxime ether derivatives prepared and examined as cytotoxic agents.