Urgent needs of low-income and middle-income countries for COVID-19 vaccines and therapeutics
J. Peter Figueroa,Maria Elena Bottazzi,Peter J. Hotez,Carolina Batista,Onder Ergonul,Sarah C. Gilbert,Mayda Gursel,Mazen Hassanain,Jerome H. Kim,Bhavna Lall,Heidi J. Larson,Denise Naniche,Timothy P. Sheahan,Shmuel Shoham,Annelies Wilder-Smith,Natalie Strub-Wourgaft,Prashant Yadav,Gagandeep Kang +17 more
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TLDR
The COVAX Facility of the ACT Accelerator has agreements to access 2 billion doses of WHO prequalified vaccines during 2021, but this represents only 20% of the vaccine needs of participating countries Most low-income and middle-income countries face difficulties in accessing and delivering vaccines and therapeutics for COVID-19 to their populations.About:
This article is published in The Lancet.The article was published on 2021-02-13 and is currently open access. It has received 98 citations till now.read more
Citations
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Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization.
Jennifer Monereo-Sánchez,Jurjen J. Luykx,Justo Pinzón-Espinosa,Justo Pinzón-Espinosa,Geneviève Richard,Ehsan Motazedi,Lars T. Westlye,Lars T. Westlye,Ole A. Andreassen,Dennis van der Meer +9 more
TL;DR: In this article, the authors used logistic regression to test whether individuals vaccinated for tetanus, diphtheria or pertussis, differed from individuals that had only received other vaccinations on 1) undergoing a COVID-19 test, 2) being diagnosed with COVID, and 3) whether they developed severe COVID19 symptoms.
Journal ArticleDOI
An Implementation Research Approach to Re-orient Health Supply Chains Toward an Equity Agenda in the COVID-19 Era.
TL;DR: The Covid-19 pandemic has exposed critical inequities in global healthcare supply chains and the need for these systems to be analyzed and reoriented with an equity lens as mentioned in this paper.
Journal ArticleDOI
A Mapping Review on the Uptake of the COVID-19 Vaccine among Adults in Africa Using the 5As Vaccine Taxonomy
Michael E Kalu,Oluwagbemiga Oyinlola,Michael C Ibekaku,Israel I Adandom,Anthony Obinna Iwuagwu,Chigozie Donatus Ezulike,Ernest C. Nwachukwu,Ekezie Mmanwanne Uduonu +7 more
TL;DR: The governments of African nations should focus on strategies to influence the modifiable factors identified in this review to improve COVID-19 vaccine uptake in African nations.
Journal ArticleDOI
Personal Narrative under Nationalism: Chinese COVID-19 Vaccination Expressions on Douyin
TL;DR: This article explored Chinese COVID-19 vaccination expressions on Douyin, China's biggest short-video sharing social media platform, and found that narration is still the most important tool employed by Chinese users when talking about COVID19 vaccinations, emphasizing nationalism and widespread optimism.
Posted ContentDOI
An adjuvanted SARS-CoV-2 RBD nanoparticle elicits neutralizing antibodies and fully protective immunity in aged mice
Francesco Borriello,Francesco Borriello,Etsuro Nanishi,Etsuro Nanishi,Hyuk-Soo Seo,Timothy R O'Meara,Marisa McGrath,Yoshine Saito,Robert Haupt,Jing Chen,Joann Diray-Arce,Joann Diray-Arce,Kijun Song,Andrew Z Xu,Timothy M. Caradonna,Jared Feldman,Blake M. Hauser,Aaron G. Schmidt,Aaron G. Schmidt,Robert K. Ernst,Carly Dillen,Stuart Weston,Robert M. Johnson,Holly L. Hammond,Jingyou Yu,Aiquan Chang,Luuk A. Th. Hilgers,Peter Paul L.I. Platenburg,Sirano Dhe-Paganon,Dan H. Barouch,Al Ozonoff,Al Ozonoff,Ivan Zanoni,Ivan Zanoni,Matthew B. Frieman,David J. Dowling,David J. Dowling,Ofer Levy,Ofer Levy,Ofer Levy +39 more
TL;DR: In this paper, a combination of SARS-CoV-2 protein antigens and adjuvants was used to identify a combination that elicits neutralizing antibodies and protection in young and aged mice.
References
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Journal ArticleDOI
Reserving coronavirus disease 2019 vaccines for global access: cross sectional analysis.
Anthony D. So,Joshua Woo +1 more
TL;DR: This study provides an overview of how high income countries have secured future supplies of covid-19 vaccines but that access for the rest of the world is uncertain.
Journal ArticleDOI
Potential effects of vaccinations on the prevention of COVID-19: rationale, clinical evidence, risks, and public health considerations.
Janet Sultana,Giampiero Mazzaglia,Nicoletta Luxi,Antonino Cancellieri,Annalisa Capuano,Carmen Ferrajolo,Chiara de Waure,Guido Ferlazzo,Gianluca Trifirò +8 more
TL;DR: This review will discuss the available immunologic and clinical evidence to support the benefit of the influenza, pneumococcal, and tuberculosis vaccines in the context of COVID-19 as well as to provide an overview on the CO VID-19-specific vaccines that are in the development pipeline.
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Report on WHO meeting on immunization in older adults: Geneva, Switzerland, 22-23 March 2017.
M. Teresa Aguado,Jane Barratt,John R. Beard,Bonnie B. Blomberg,Wilbur H. Chen,Julian Hickling,Terri B. Hyde,Mark Jit,Mark Jit,Rebecca Jones,Gregory A. Poland,Martin Friede,Justin R. Ortiz +12 more
TL;DR: There is a need for discussion of new opportunities for vaccinations of all adults as well as for vaccination of older adults, as reflected in the recent shift by WHO to a life-course approach to immunization.
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Strengthening medical product regulation in low- and middle-income countries.
TL;DR: Charles Preston and colleagues use case studies to describe how regulatory systems for medical products and medicines must be strengthened in low and middle income countries to assure adequate quality, safety and efficacy.
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