L
Lars T. Westlye
Researcher at University of Oslo
Publications - 473
Citations - 25065
Lars T. Westlye is an academic researcher from University of Oslo. The author has contributed to research in topics: Medicine & Cognition. The author has an hindex of 68, co-authored 398 publications receiving 18911 citations. Previous affiliations of Lars T. Westlye include Indiana University & University of California, San Diego.
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Journal ArticleDOI
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium
T.G.M. van Erp,Derrek P. Hibar,Jerod M. Rasmussen,David C. Glahn,Godfrey D. Pearlson,Ole A. Andreassen,Ingrid Agartz,Ingrid Agartz,Lars T. Westlye,Lars T. Westlye,Unn K. Haukvik,Anders M. Dale,Ingrid Melle,Cecilie B. Hartberg,Oliver Gruber,Bernd Kraemer,David Zilles,Gary Donohoe,Gary Donohoe,Sinead Kelly,Sinead Kelly,Colm McDonald,Derek W. Morris,Derek W. Morris,Dara M. Cannon,Aiden Corvin,Marise W. J. Machielsen,Laura Koenders,L. de Haan,Dick J. Veltman,Theodore D. Satterthwaite,Daniel H. Wolf,R.C. Gur,R.E. Gur,Steven G. Potkin,Daniel H. Mathalon,Daniel H. Mathalon,Bryon A. Mueller,Adrian Preda,Fabio Macciardi,Stefan Ehrlich,Stefan Ehrlich,Esther Walton,Johanna Hass,Vince D. Calhoun,HJ Bockholt,Scott R. Sponheim,Jody M. Shoemaker,N.E.M. van Haren,Hilleke E. Hulshoff Pol,Roel A. Ophoff,Roel A. Ophoff,René S. Kahn,Roberto Roiz-Santiañez,Benedicto Crespo-Facorro,Lei Wang,Kathryn I. Alpert,Erik G. Jönsson,Erik G. Jönsson,Rali Dimitrova,Catherine Bois,Heather C. Whalley,Andrew M. McIntosh,Stephen M. Lawrie,Ryota Hashimoto,Paul M. Thompson,Jessica A. Turner +66 more
TL;DR: Worldwide cooperative analyses of brain imaging data support a profile of subcortical abnormalities in schizophrenia, which is consistent with that based on traditional meta-analytic approaches, and validates that collaborative data analyses can readily be used across brain phenotypes and disorders.
Journal ArticleDOI
Brain Maturation in Adolescence and Young Adulthood: Regional Age-Related Changes in Cortical Thickness and White Matter Volume and Microstructure
Christian K. Tamnes,Ylva Østby,Anders M. Fjell,Lars T. Westlye,Paulina Due-Tønnessen,Kristine B. Walhovd +5 more
TL;DR: The results indicate that cortical thinning in adolescence cannot be explained by WM maturation in underlying regions as measured by volumetry or DTI, and that the integration of the 3 measures will yield a more complete understanding of brain maturation.
Journal ArticleDOI
Common genetic variants influence human subcortical brain structures.
Derrek P. Hibar,Jason L. Stein,Jason L. Stein,Miguel E. Rentería,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Roberto Toro,Katharina Wittfeld,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Manon Bernard,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Andrew A. Brown,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil Lee,Phil Lee,Loes M. Olde Loohuis,Michelle Luciano,Christine Macare,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Shannon L. Risacher,Roberto Roiz-Santiañez,Emma J. Rose,Alireza Salami,Alireza Salami,Philipp G. Sämann,Lianne Schmaal,Andrew J. Schork,Jean Shin,Lachlan T. Strike,Lachlan T. Strike,Alexander Teumer,Marjolein M.J. van Donkelaar,Kristel R. van Eijk,Raymond K. Walters,Raymond K. Walters,Lars T. Westlye,Christopher D. Whelan,Anderson M. Winkler,Anderson M. Winkler,Marcel P. Zwiers,Saud Alhusaini,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Stefan Ehrlich,Marina Hakobjan,Cecilie B. Hartberg,Unn K. Haukvik,Angelien Heister,D. Hoehn,Dalia Kasperaviciute,Dalia Kasperaviciute,David C. Liewald,Lorna M. Lopez,Remco R. R. Makkinje,Mar Matarin,Marlies Naber,D. Reese McKay,Margaret Needham,Allison C. Nugent,Benno Pütz,Natalie A. Royle,Li Shen,Emma Sprooten,Emma Sprooten,Daniah Trabzuni,Daniah Trabzuni,Saskia S. L. van der Marel,Kimm J. E. van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,Laura Almasy,David Ames,David Ames,Sampath Arepalli,Amelia A. Assareh,Mark E. Bastin,Henry Brodaty,Kazima B. Bulayeva,Melanie A. Carless,Sven Cichon,Sven Cichon,Aiden Corvin,Joanne E. Curran,Michael Czisch,Greig I. de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D. Dyer,Thomas D. Dyer,Susanne Erk,Iryna O. Fedko,Luigi Ferrucci,Tatiana Foroud,Peter T. Fox,Peter T. Fox,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,Harald H H Göring,Robert C. Green,Sebastian Guelfi,Narelle K. Hansell,Catharina A. Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Pieter J. Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Ryota Kanai,Maria Keil,Jack W. Kent,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Xinmin Liu,Xinmin Liu,Dan L. Longo,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W. Montgomery,Jeanette C. Mostert,Thomas W. Mühleisen,Mike A. Nalls,Thomas E. Nichols,Thomas E. Nichols,Lars Nilsson,Markus M. Nöthen,Kazutaka Ohi,Rene L. Olvera,Rocío Pérez-Iglesias,G. Bruce Pike,Steven G. Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D. Rosen,Dan Rujescu,Knut Schnell,Peter R. Schofield,Peter R. Schofield,Colin Smith,Vidar M. Steen,Jessika E. Sussmann,Anbupalam Thalamuthu,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Jessica A. Turner,Maria C. Valdés Hernández,Dennis van 't Ent,Marcel P. van der Brug,Nic J.A. van der Wee,Marie-José van Tol,Dick J. Veltman,Thomas H. Wassink,Eric Westman,Ronald H. Zielke,Alan B. Zonderman,David G. Ashbrook,Reinmar Hager,Lu Lu,Lu Lu,Francis J. McMahon,Derek W. Morris,Derek W. Morris,Robert W. Williams,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Wiepke Cahn,Vince D. Calhoun,Vince D. Calhoun,Gianpiero L. Cavalleri,Benedicto Crespo-Facorro,Anders M. Dale,Gareth E. Davies,Norman Delanty,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Thomas Espeseth,Randy L. Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Wolfgang Hoffmann,Norbert Hosten,René S. Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W.J.H. Penninx,Joshua L. Roffman,Sanjay M. Sisodiya,Jordan W. Smoller,Jordan W. Smoller,Hans van Bokhoven,Neeltje E.M. van Haren,Henry Völzke,Henrik Walter,Michael W. Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ingrid Agartz,Ole A. Andreassen,John Blangero,John Blangero,Dorret I. Boomsma,Rachel M. Brouwer,Dara M. Cannon,Dara M. Cannon,Mark R. Cookson,Eco J. C. de Geus,Ian J. Deary,Gary Donohoe,Gary Donohoe,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Clyde Francks,Clyde Francks,David C. Glahn,Hans J. Grabe,Oliver Gruber,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E. Hulshoff Pol,Erik G. Jönsson,Erik G. Jönsson,Iwona Kłoszewska,Simon Lovestone,Simon Lovestone,Venkata S. Mattay,Patrizia Mecocci,Colm McDonald,Andrew M. McIntosh,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Andrew Simmons,Andrew B. Singleton,Hilkka Soininen,Joanna M. Wardlaw,Michael E. Weale,Daniel R. Weinberger,Hieab H.H. Adams,Lenore J. Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L. Satizabal,Claudia L. Satizabal,James T. Becker,Lisa R. Yanek,Sven J. van der Lee,Maritza Ebling,Bruce Fischl,Bruce Fischl,W. T. Longstreth,Douglas N. Greve,Helena Schmidt,Paul A. Nyquist,Louis N. Vinke,Cornelia M. van Duijn,Luting Xue,Bernard Mazoyer,Joshua C. Bis,Vilmundur Gudnason,Sudha Seshadri,Sudha Seshadri,M. Arfan Ikram,Nicholas G. Martin,Margaret J. Wright,Margaret J. Wright,Gunter Schumann,Barbara Franke,Barbara Franke,Paul M. Thompson,Sarah E. Medland +344 more
TL;DR: In this paper, the authors conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magnetic resonance images of 30,717 individuals from 50 cohorts.
Journal ArticleDOI
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Paul M. Thompson,Jason L. Stein,Sarah E. Medland,Derrek P. Hibar,Alejandro Arias Vasquez,Miguel E. Rentería,Roberto Toro,Neda Jahanshad,Gunter Schumann,Barbara Franke,Margaret J. Wright,Nicholas G. Martin,Ingrid Agartz,Ingrid Agartz,Martin Alda,Saud Alhusaini,Saud Alhusaini,Laura Almasy,Jorge R. C. Almeida,Jorge R. C. Almeida,Jorge R. C. Almeida,Kathryn I. Alpert,Nancy C. Andreasen,Ole A. Andreassen,Liana G. Apostolova,Katja Appel,Nicola J. Armstrong,Benjamin S. Aribisala,Mark E. Bastin,Michael Bauer,Carrie E. Bearden,Ørjan Bergmann,Elisabeth B. Binder,John Blangero,HJ Bockholt,Erlend Bøen,Catherine Bois,Dorret I. Boomsma,Tom Booth,Ian Bowman,Janita Bralten,Rachel M. Brouwer,Han G. Brunner,David G. Brohawn,Randy L. Buckner,Jan K. Buitelaar,Kazima B. Bulayeva,Juan R. Bustillo,Vince D. Calhoun,Vince D. Calhoun,Dara M. Cannon,Rita M. Cantor,Melanie A. Carless,Xavier Caseras,Gianpiero L. Cavalleri,M. Mallar Chakravarty,Kiki D. Chang,Christopher R.K. Ching,Andrea Christoforou,Andrea Christoforou,Sven Cichon,Sven Cichon,Vincent P. Clark,Patricia J. Conrod,Patricia J. Conrod,Giovanni Coppola,Benedicto Crespo-Facorro,Joanne E. Curran,Michael Czisch,Ian J. Deary,Eco J. C. de Geus,Anouk den Braber,G. Delvecchio,Chantal Depondt,Lieuwe de Haan,Lieuwe de Haan,Greig I. de Zubicaray,Danai Dima,Rali Dimitrova,Srdjan Djurovic,Hong-Wei Dong,Gary Donohoe,Gary Donohoe,Ravindranath Duggirala,Thomas D. Dyer,Stefan Ehrlich,Stefan Ehrlich,Carl Johan Ekman,Torbjørn Elvsåshagen,Louise Emsell,Susanne Erk,Thomas Espeseth,Jesen Fagerness,Scott C. Fears,Iryna O. Fedko,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Tatiana Foroud,Peter T. Fox,Clyde Francks,Clyde Francks,Sophia Frangou,Eva Maria Frey,Thomas Frodl,Thomas Frodl,Vincent Frouin,Hugh Garavan,Sudheer Giddaluru,David C. Glahn,Beata R. Godlewska,Rita Z. Goldstein,Randy L. Gollub,Hans J. Grabe,Oliver Grimm,Oliver Gruber,Tulio Guadalupe,Raquel E. Gur,Ruben C. Gur,Ruben C. Gur,Harald H H Göring,Saskia P. Hagenaars,Tomas Hajek,Geoffrey B. Hall,Jeremy Hall,Jeremy Hall,John Hardy,Catharina A. Hartman,Johanna Hass,Sean N. Hatton,Unn K. Haukvik,K Hegenscheid,Andreas Heinz,Ian B. Hickie,Beng-Choon Ho,D. Hoehn,Pieter J. Hoekstra,Marisa O. Hollinshead,Avram J. Holmes,Georg Homuth,Martine Hoogman,L. Elliot Hong,Norbert Hosten,Jouke-Jan Hottenga,Hilleke E. Hulshoff Pol,Kristy S. Hwang,Clifford R. Jack,Mark Jenkinson,Caroline Johnston,Caroline Johnston,Erik G. Jönsson,René S. Kahn,Dalia Kasperaviciute,Sinead Kelly,Sungeun Kim,Peter Kochunov,Laura Koenders,Laura Koenders,Bernd Krämer,John B.J. Kwok,John B.J. Kwok,Jim Lagopoulos,Gonzalo Laje,Mikael Landén,Mikael Landén,Bennett A. Landman,John Lauriello,Stephen M. Lawrie,Phil Lee,Phil Lee,Stephanie Le Hellard,Stephanie Le Hellard,Herve Lemaitre,Cassandra D. Leonardo,Chiang shan Li,Benny Liberg,David C. Liewald,Xinmin Liu,Xinmin Liu,Lorna M. Lopez,Eva Loth,Anbarasu Lourdusamy,Michelle Luciano,Fabio Macciardi,Fabio Macciardi,Marise W. J. Machielsen,Marise W. J. Machielsen,Glenda MacQueen,Ulrik Fredrik Malt,René C.W. Mandl,Dara S. Manoach,Jean-Luc Martinot,Mar Matarin,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Morten Mattingsdal,Andreas Meyer-Lindenberg,Colm McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Yuri Milaneschi,Yuri Milaneschi,Sebastian Mohnke,Grant W. Montgomery,Derek W. Morris,Eric K. Moses,Eric K. Moses,Bryon A. Mueller,Susana Muñoz Maniega,Thomas W. Mühleisen,Bertram Müller-Myhsok,Benson Mwangi,Matthias Nauck,Kwangsik Nho,Thomas E. Nichols,Lars-Göran Nilsson,Lars-Göran Nilsson,Allison C. Nugent,Lars Nyberg,Rene L. Olvera,Jaap Oosterlaan,Roel A. Ophoff,Roel A. Ophoff,Massimo Pandolfo,Melina Papalampropoulou-Tsiridou,Martina Papmeyer,Tomáš Paus,Zdenka Pausova,Godfrey D. Pearlson,Godfrey D. Pearlson,Brenda W.J.H. Penninx,Charles P. Peterson,Andrea Pfennig,Mary L. Phillips,G. Bruce Pike,Jean-Baptiste Poline,Steven G. Potkin,Benno Pütz,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Jerod M. Rasmussen,Marcella Rietschel,Mark Rijpkema,Shannon L. Risacher,Joshua L. Roffman,Roberto Roiz-Santiañez,Nina Romanczuk-Seiferth,Emma J. Rose,Natalie A. Royle,Dan Rujescu,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Alireza Salami,Alireza Salami,Theodore D. Satterthwaite,Jonathan Savitz,Jonathan Savitz,Andrew J. Saykin,Cathy Scanlon,Lianne Schmaal,Hugo G. Schnack,Andrew J. Schork,S. Charles Schulz,Remmelt R. Schür,Larry J. Seidman,Li Shen,Jody M. Shoemaker,Andrew Simmons,Andrew Simmons,Sanjay M. Sisodiya,Colin Smith,Jordan W. Smoller,Jordan W. Smoller,Jair C. Soares,Scott R. Sponheim,Scott R. Sponheim,Emma Sprooten,John M. Starr,Vidar M. Steen,Vidar M. Steen,Stephen M. Strakowski,Lachlan T. Strike,Jessika E. Sussmann,Philipp G. Sämann,Alexander Teumer,Arthur W. Toga,Diana Tordesillas-Gutiérrez,Daniah Trabzuni,Daniah Trabzuni,Sarah Trost,Jessica A. Turner,Jessica A. Turner,Martijn P. van den Heuvel,Nic J.A. van der Wee,Kristel R. van Eijk,Theo G.M. van Erp,Neeltje E.M. van Haren,Dennis van 't Ent,Marie-José van Tol,Maria C. Valdés Hernández,Dick J. Veltman,Amelia Versace,Henry Völzke,Robert Walker,Henrik Walter,Henrik Walter,Lei Wang,Joanna M. Wardlaw,Michael E. Weale,Michael W. Weiner,Wei Wen,Lars T. Westlye,Heather C. Whalley,Christopher D. Whelan,Tonya White,Anderson M. Winkler,Anderson M. Winkler,Katharina Wittfeld,Girma Woldehawariat,Christiane Wolf,David Zilles,Marcel P. Zwiers,Anbupalam Thalamuthu,Peter R. Schofield,Peter R. Schofield,Nelson B. Freimer,Natalia Lawrence,Wayne C. Drevets +332 more
TL;DR: The ENIGMA Consortium has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected.
Journal ArticleDOI
Life-Span Changes of the Human Brain White Matter: Diffusion Tensor Imaging (DTI) and Volumetry
Lars T. Westlye,Kristine B. Walhovd,Anders M. Dale,Anders M. Dale,Atle Bjørnerud,Paulina Due-Tønnessen,Andreas Engvig,Håkon Grydeland,Christian K. Tamnes,Ylva Østby,Anders M. Fjell +10 more
TL;DR: Although the volumetric data supported protracted growth into the sixth decade, DTI indices plateaued early in the fourth decade and then declined slowly into late adulthood followed by an accelerating decrease in senescence, providing insufficient evidence in support of a simple last-in-first-out hypothesis of life-span changes.