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Journal ArticleDOI

Usefulness of Age (≥85 Years) and Residual Mitral Regurgitation (>1+/4+) for the Prediction of Adverse Outcomes in Patients Receiving the MitraClip.

Wei Chen, +9 more
- 01 Nov 2019 - 
- Vol. 124, Iss: 9, pp 1449-1453
TLDR
A reduced left ventricular end-diastolic volume and improved hemodynamics occurred early after MitraClip therapy, and an advanced age and residual MR >1+ were associated with an increased risk of mortality and heart failure.
Abstract: 
The goal of this study was to determine the predictors of adverse clinical outcomes in patients treated with the MitraClip for significant mitral regurgitation (MR) with a focus on acute changes in hemodynamics and cardiac function. This retrospective study included 63 patients (mean age 82 ± 8 years, 48% male) with moderate to severe or severe MR. Cardiac catheterization was performed before and immediately after MitraClip repair. Volumetric and functional changes were assessed in both ventricles. A major adverse cardiac event was defined as a composite of cardiac death and readmission for heart failure. Patients were followed up on average for 380 days. MR was improved in 92% of patients after MitraClip therapy from an average grade of 4+ to 1+ (p 1+ were associated with an increased risk of mortality and heart failure.

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Citations
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Journal ArticleDOI

Characteristics and outcomes of MitraClip in octogenarians: Evidence from 1853 patients in the GIOTTO registry.

Arturo Giordano, +21 more
- 01 Nov 2021 - 
TL;DR: In this paper, the authors evaluated features and outcomes of patients undergoing MitraClip treatment according to their age and concluded that mitral valve repair with the mitra-clip in carefully selected octogenarians appears feasible and safe, and is associated with favorable clinical outcomes at mid-term follow-up.
Journal ArticleDOI

Transcatheter mitral valve repair is feasible and effective in oldest-old patients: results from real-world cohort.

Mhd Nawar Alachkar, +7 more
- 28 Oct 2022 - 
TL;DR: In this paper , the authors evaluated the safety and efficacy of transcatheter mitral valve repair (TMVR) using MitraClip® devices in oldest-old patients compared to younger patients.
Journal ArticleDOI

Severe mitral regurgitation in nonagenarians: Impact of symptomatic status, frailty and etiology on management and outcomes.

Alejandro Duran Crane, +11 more
- 01 Jan 2023 - 
TL;DR: In this paper , the authors assess symptomatic status, frailty, etiology and outcomes for nonagenarians with severe mitral regurgitation (MR) in extremely elderly patients.
References
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Journal ArticleDOI

Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.

Roberto M. Lang, +17 more
- 01 Jan 2015 - 
TL;DR: This document provides updated normal values for all four cardiac chambers, including three-dimensional echocardiography and myocardial deformation, when possible, on the basis of considerably larger numbers of normal subjects, compiled from multiple databases.
Journal ArticleDOI

2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Rick A. Nishimura, +12 more
- 11 Jul 2017 - 
TL;DR: In this article, Levine and O'Gara proposed a new chairperson for FAHA, who was elected by a majority of the FAHA board members, including Birtcher, Bozkurt and Halperin.
Journal ArticleDOI

Transcatheter Mitral-Valve Repair in Patients with Heart Failure.

Gregg W. Stone, +16 more
- 23 Sep 2018 - 
TL;DR: Among patients with heart failure and moderate‐to‐severe or severe secondary mitral regurgitation who remained symptomatic despite the use of maximal doses of guideline‐directed medical therapy, transcatheter mitral‐valve repair resulted in a lower rate of hospitalization forHeart failure and lower all‐cause mortality within 24 months of follow‐up than medical therapy alone.
Journal ArticleDOI

Percutaneous Repair or Surgery for Mitral Regurgitation

Ted Feldman, +16 more
- 13 Apr 2011 - 
TL;DR: Although percutaneous repair was less effective at reducing mitral regurgitation than conventional surgery, the procedure was associated with superior safety and similar improvements in clinical outcomes.
Journal ArticleDOI

Percutaneous mitral repair with the MitraClip system: safety and midterm durability in the initial EVEREST (Endovascular Valve Edge-to-Edge REpair Study) cohort.

Ted Feldman, +13 more
- 18 Aug 2009 - 
TL;DR: Percutaneous repair with the MitraClip system can be accomplished with low rates of morbidity and mortality and with acute MR reduction to < 2+ in the majority of patients, and with sustained freedom from death, surgery, or recurrent MR in a substantial proportion.
Related Papers (5)

MitraClip therapy and surgical edge-to-edge repair in patients with severe left ventricular dysfunction and secondary mitral regurgitation: mid-term results of a single-centre experience†.

Michele De Bonis, +10 more
- 01 Jan 2016 - 

Meta-analysis of the usefulness of Mitraclip in patients with functional mitral regurgitation.

Fabrizio D'Ascenzo, +22 more
- 15 Jul 2015 - 

Percutaneous mitral repair with the MitraClip system in patients with mild-to-moderate and severe heart failure: a single-centre experience.

Ilkay Bozdag-Turan, +11 more
- 01 Apr 2014 - 

Transcatheter Repair of Functional Mitral Regurgitation in Heart Failure Patients - A Meta-Analysis of 23 Studies on MitraClip Implantation.

Roberta De Rosa, +10 more
- 25 Oct 2018 - 

Predictors of outcome in heart failure patients with severe functional mitral regurgitation undergoing MitraClip treatment.

Cesare Baldi, +11 more
- 01 Jun 2019 -