Albert Blanco-Grau

TL;DR: A 3p21.31 gene cluster is identified as a genetic susceptibility locus in patients with Covid-19 with respiratory failure and a potential involvement of the ABO blood-group system is confirmed.

TL;DR: Posaconazole showed antitrypanosomal activity in patients with chronic Chagas' disease, however, significantly more patients in the posaconazoles groups than in the benznidazole group had treatment failure during follow-up.

TL;DR: The first robust genetic susceptibility loci for the development of respiratory failure in Covid-19 are reported, and Identified variants may help guide targeted exploration of severe Covd-19 pathophysiology.

TL;DR: An extended GWAS meta-analysis of a well-characterized cohort of COVID-19 patients with respiratory failure and population controls from Italy, Spain, Norway and Germany/Austria, including stratified analyses based on age, sex and disease severity, as well as targeted analyses of chromosome Y haplotypes, the human leukocyte antigen (HLA) region and the SARS-CoV-2 peptidome is described.

TL;DR: Medical test results following a normal distribution showed comparable and consistent reference intervals between studies, and a simple indirect method is a feasible and cost-efficient approach for calculating reference intervals.