A
Alessandra Serio
Researcher at Foundation University, Islamabad
Publications - 46
Citations - 2989
Alessandra Serio is an academic researcher from Foundation University, Islamabad. The author has contributed to research in topics: Heart failure & Cardiomyopathy. The author has an hindex of 20, co-authored 43 publications receiving 2668 citations. Previous affiliations of Alessandra Serio include University of Pavia.
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Journal ArticleDOI
Atlas of the clinical genetics of human dilated cardiomyopathy
Jan Haas,Karen S. Frese,Barbara Peil,Wanda Kloos,Andreas Keller,Rouven Nietsch,Zhu Feng,Sabine Müller,Elham Kayvanpour,Britta Vogel,Farbod Sedaghat-Hamedani,Wei Keat Lim,Xiaohong Zhao,Dmitriy Fradkin,Doreen Köhler,Simon Fischer,Jennifer Franke,Sabine Marquart,Ioana Barb,Daniel Tian Li,Ali Amr,Philipp Ehlermann,Derliz Mereles,Tanja Weis,Sarah Hassel,Andreas Kremer,Vanessa King,Emil Wirsz,Emil Wirsz,Richard Isnard,Michel Komajda,Alessandra Serio,Maurizia Grasso,Petros Syrris,Eleanor Wicks,Vincent Plagnol,Luis R. Lopes,Tenna Gadgaard,Hans Eiskjær,Mads E. Jørgensen,Diego García-Giustiniani,Martin Ortiz-Genga,María G. Crespo-Leiro,Rondal H Lekanne Dit Deprez,Imke Christiaans,Ingrid A.W. van Rijsingen,Arthur A.M. Wilde,Anders Waldenström,Martino Bolognesi,Riccardo Bellazzi,Stellan Mörner,Justo Lorenzo Bermejo,Lorenzo Monserrat,Eric Villard,Jens Mogensen,Yigal M. Pinto,Philippe Charron,Perry M. Elliott,Eloisa Arbustini,Hugo A. Katus,Benjamin Meder +60 more
TL;DR: This is to the authors' knowledge, the first study that comprehensively investigated the genetics of DCM in a large-scale cohort and across a broad gene panel of the known DCM genes and underline the high analytical quality and feasibility of Next-Generation Sequencing in clinical genetic diagnostics.
Journal ArticleDOI
Long-term outcome and risk stratification in dilated cardiolaminopathies.
Michele Pasotti,Catherine Klersy,Andrea Pilotto,Nicola Marziliano,Claudio Rapezzi,Alessandra Serio,Savina Mannarino,Fabiana Isabella Gambarin,Valentina Favalli,Maurizia Grasso,Manuela Agozzino,Carlo Campana,Antonello Gavazzi,Oreste Febo,Massimiliano Marini,Maurizio Landolina,Andrea Mortara,Giovanni Piccolo,Mario Viganò,Luigi Tavazzi,Eloisa Arbustini +20 more
TL;DR: Dilated cardiomyopathies caused by LMNA gene defects are highly penetrant, adult onset, malignant diseases characterized by a high rate of heart failure and life-threatening arrhythmias, predicted by New York Heart Association functional class, competitive sport activity, and type of mutation.
Journal ArticleDOI
Interventricular and intraventricular dyssynchrony are common in heart failure patients, regardless of QRS duration
Stefano Ghio,Cristina Constantin,Catherine Klersy,Alessandra Serio,Alessandra Fontana,Carlo Campana,Luigi Tavazzi +6 more
TL;DR: A substantial proportion of heart failure patients with a slightly prolonged QRS or even with normal conduction may exhibit ventricular dyssynchrony, and both standard echocardiography and tissue Doppler imaging are necessary to describe the entire spectrum of mechanical abnormalities due to dyss synchrony.
Journal ArticleDOI
Prognostic relevance of the echocardiographic assessment of right ventricular function in patients with idiopathic pulmonary arterial hypertension.
Stefano Ghio,Catherine Klersy,Giulia Magrini,Andrea Maria D'Armini,Laura Scelsi,Claudia Raineri,Michele Pasotti,Alessandra Serio,Carlo Campana,Mario Viganò +9 more
TL;DR: A comprehensive echocardiographic assessment of RV systolic and diastolic function based on TAPSE, left ventricular diastolics eccentricity index and degree of tricuspid regurgitation allows an accurate prognostic stratification of patients with idiopathic pulmonary hypertension.
Journal ArticleDOI
Left Ventricular Noncompaction : A Distinct Genetic Cardiomyopathy?
TL;DR: The prevalence of LVNC in healthy athletes, its possible reversibility, and increasing diagnosis in healthy subjects suggests cautious use of the term LVNC cardiomyopathy, which describes the morphology but not the functional profile of the cardiopathy.