J
Justo Lorenzo Bermejo
Researcher at Heidelberg University
Publications - 235
Citations - 7151
Justo Lorenzo Bermejo is an academic researcher from Heidelberg University. The author has contributed to research in topics: Cancer & Population. The author has an hindex of 45, co-authored 227 publications receiving 6211 citations. Previous affiliations of Justo Lorenzo Bermejo include Karolinska Institutet & German Cancer Research Center.
Papers
More filters
Journal ArticleDOI
Atlas of the clinical genetics of human dilated cardiomyopathy
Jan Haas,Karen S. Frese,Barbara Peil,Wanda Kloos,Andreas Keller,Rouven Nietsch,Zhu Feng,Sabine Müller,Elham Kayvanpour,Britta Vogel,Farbod Sedaghat-Hamedani,Wei Keat Lim,Xiaohong Zhao,Dmitriy Fradkin,Doreen Köhler,Simon Fischer,Jennifer Franke,Sabine Marquart,Ioana Barb,Daniel Tian Li,Ali Amr,Philipp Ehlermann,Derliz Mereles,Tanja Weis,Sarah Hassel,Andreas Kremer,Vanessa King,Emil Wirsz,Emil Wirsz,Richard Isnard,Michel Komajda,Alessandra Serio,Maurizia Grasso,Petros Syrris,Eleanor Wicks,Vincent Plagnol,Luis R. Lopes,Tenna Gadgaard,Hans Eiskjær,Mads E. Jørgensen,Diego García-Giustiniani,Martin Ortiz-Genga,María G. Crespo-Leiro,Rondal H Lekanne Dit Deprez,Imke Christiaans,Ingrid A.W. van Rijsingen,Arthur A.M. Wilde,Anders Waldenström,Martino Bolognesi,Riccardo Bellazzi,Stellan Mörner,Justo Lorenzo Bermejo,Lorenzo Monserrat,Eric Villard,Jens Mogensen,Yigal M. Pinto,Philippe Charron,Perry M. Elliott,Eloisa Arbustini,Hugo A. Katus,Benjamin Meder +60 more
TL;DR: This is to the authors' knowledge, the first study that comprehensively investigated the genetics of DCM in a large-scale cohort and across a broad gene panel of the known DCM genes and underline the high analytical quality and feasibility of Next-Generation Sequencing in clinical genetic diagnostics.
Journal ArticleDOI
Systems-wide proteomic analysis in mammalian cells reveals conserved, functional protein turnover.
Sidney B. Cambridge,Florian Gnad,Chuong Nguyen,Justo Lorenzo Bermejo,Marcus Krüger,Matthias Mann +5 more
TL;DR: High-resolution mass spectrometry was employed to quantify protein dynamics in nondividing mammalian cells and observed statistically significant trends for the turnover of phosphoproteins and gene ontology categories that showed extensive covariation between mouse and human.
Journal ArticleDOI
The balance between heritable and environmental aetiology of human disease.
TL;DR: Using cancer as an example of complex disease, the scientific evidence for the hypothesis that human diseases result from interactions between genetic variants and the environment is examined.
Journal ArticleDOI
Methylome analysis and integrative profiling of human HCCs identify novel protumorigenic factors.
Olaf Neumann,Miriam Kesselmeier,Robert Geffers,R Pellegrino,Bernhard Radlwimmer,Katrin Hoffmann,Volker Ehemann,Peter Schemmer,Peter Schirmacher,Justo Lorenzo Bermejo,Thomas Longerich +10 more
TL;DR: It is illustrated that vertical integration of methylation data with high‐resolution genomic and transcriptomic data facilitates the identification of new tumor‐suppressor gene candidates in human HCC.
Journal ArticleDOI
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy
Benjamin Meder,Frank Rühle,Tanja Weis,Georg Homuth,Andreas Keller,Jennifer Franke,Barbara Peil,Justo Lorenzo Bermejo,Karen S. Frese,Andreas Huge,Anika Witten,Britta Vogel,Jan Haas,Uwe Völker,Florian Ernst,Alexander Teumer,Philipp Ehlermann,Christian Zugck,Frauke Friedrichs,Heyo K. Kroemer,Marcus Dörr,Wolfgang Hoffmann,Bernhard Maisch,Sabine Pankuweit,Volker Ruppert,Thomas Scheffold,Uwe Kühl,H.P. Schultheiss,Reinhold Kreutz,Georg Ertl,Christiane E. Angermann,Philippe Charron,Eric Villard,Françoise Gary,Richard Isnard,Michel Komajda,Matthias Lutz,Thomas Meitinger,Moritz F. Sinner,Moritz F. Sinner,Moritz F. Sinner,H.-Erich Wichmann,Michael Krawczak,Boris Ivandic,Dieter Weichenhan,Goetz Gelbrich,Nour Eddine El-Mokhtari,Stefan Schreiber,Stephan B. Felix,Gerd Hasenfuß,Arne Pfeufer,Norbert Hubner,Stefan Kääb,Eloisa Arbustini,Wolfgang Rottbauer,Wolfgang Rottbauer,Norbert Frey,Norbert Frey,Monika Stoll,Hugo A. Katus +59 more
TL;DR: The present study reveals a novel genetic susceptibility locus that clearly underlines the role of genetically driven, inflammatory processes in the pathogenesis of idiopathic DCM.