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Andrew Barr
Researcher at Newcastle upon Tyne Hospitals NHS Foundation Trust
Publications - 6
Citations - 507
Andrew Barr is an academic researcher from Newcastle upon Tyne Hospitals NHS Foundation Trust. The author has contributed to research in topics: Intensive care & Haematopoiesis. The author has an hindex of 6, co-authored 6 publications receiving 111 citations.
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Journal ArticleDOI
Single-cell multi-omics analysis of the immune response in COVID-19.
Emily Stephenson,Gary Reynolds,Rachel A. Botting,Fernando J Calero-Nieto,Michael D Morgan,Michael D Morgan,Zewen K. Tuong,Zewen K. Tuong,Karsten Bach,Karsten Bach,Waradon Sungnak,Kaylee B Worlock,Masahiro Yoshida,Natsuhiko Kumasaka,Katarzyna D. Kania,Justin Engelbert,Bayanne Olabi,Jarmila Stremenova Spegarova,Nicola K. Wilson,Nicole Mende,Laura Jardine,Louis C.S. Gardner,Issac Goh,Dave Horsfall,Jim McGrath,Simone Webb,Michael W. Mather,Rik G.H. Lindeboom,Emma Dann,Ni Huang,Krzysztof Polanski,Elena Prigmore,Florian Gothe,Florian Gothe,Jonathan M. Scott,Rebecca Payne,Kenneth F Baker,Kenneth F Baker,Aidan T Hanrath,Aidan T Hanrath,Ina Schim van der Loeff,Andrew Barr,Amada Sanchez-Gonzalez,Laura Bergamaschi,Federica Mescia,Josephine Barnes,Eliz Kilich,Angus de Wilton,A Saigal,Aarash Saleh,Sam M. Janes,Sam M. Janes,Claire Smith,Nusayhah Gopee,Caroline Wilson,Caroline Wilson,Paul Coupland,Jonathan Coxhead +57 more
TL;DR: In this article, the authors performed single-cell transcriptome, surface proteome and T and B lymphocyte antigen receptor analyses of over 780,000 peripheral blood mononuclear cells from a cross-sectional cohort of 130 patients with varying severities of COVID-19.
Journal ArticleDOI
Co-infection in critically ill patients with COVID-19: an observational cohort study from England.
Vadsala Baskaran,Vadsala Baskaran,Hannah Lawrence,Hannah Lawrence,Louise Lansbury,Karmel Webb,Shahideh Safavi,Shahideh Safavi,Nurul I. Zainuddin,Tausif Huq,Charlotte Eggleston,Jayne Ellis,Clare Thakker,Bethan Charles,Sara E Boyd,Sara E Boyd,Tom Williams,Claire Phillips,Ethan Redmore,Sarah Platt,Eve Hamilton,Andrew Barr,Lucy Venyo,Peter R. Wilson,Tom Bewick,Priya Daniel,Paul Dark,Paul Dark,Adam R Jeans,Jamie McCanny,Jonathan D. Edgeworth,Martin J. Llewelyn,Matthias Schmid,Tricia M. McKeever,Tricia M. McKeever,Martin Beed,Wei Shen Lim,Wei Shen Lim +37 more
TL;DR: In this article, a retrospective cohort study of adults with COVID-19 admitted to seven intensive care units (ICUs) in England up to 18 May 2020, was performed, where the proportion and type of organisms were determined at 48 h following hospital admission, corresponding to community and hospital-acquired co-infections.
Posted ContentDOI
Co-infection in critically ill patients with COVID-19: An observational cohort study from England
Vadsala Baskaran,Vadsala Baskaran,Hannah Lawrence,Hannah Lawrence,Louise Lansbury,Karmel Webb,Shahideh Safavi,Shahideh Safavi,Izzah Zainuddin,Tausif Huq,Charlotte Eggleston,Jayne Ellis,Clare Thakker,Bethan Charles,Sara E Boyd,Sara E Boyd,Tom Williams,Claire Phillips,Ethan Redmore,Sarah Platt,Eve Hamilton,Andrew Barr,Lucy Venyo,Peter R. Wilson,Tom Bewick,Priya Daniel,Paul Dark,Paul Dark,Adam R Jeans,Jamie McCanny,Jonathan D. Edgeworth,Martin J. Llewelyn,Matthias Schmid,Tricia M. McKeever,Tricia M. McKeever,Martin Beed,Wei Shen Lim,Wei Shen Lim +37 more
TL;DR: Limited evidence for community-acquired bacterial co-infection in hospitalised adults with COVID-19 is found, but a high rate of Gram-negative infection acquired during ICU stay is found.
Posted ContentDOI
COVID-19 management in a UK NHS Foundation Trust with a High Consequence Infectious Diseases centre: a detailed descriptive analysis
Kenneth F Baker,Aidan T Hanrath,Ina Schim van der Loeff,Su Ann Tee,Richard Capstick,Gabriella Marchitelli,Ang Li,Andrew Barr,Alsafi Eid,Sajeel Ahmed,Dalvir Bajwa,Omer Mohammed,Neil Alderson,Clare Lendrem,Dennis Lendrem,Lucia Pareja-Cebrian,A. R. Welch,Joanne Field,Brendan A I Payne,Yusri Taha,David Price,Chris Gibbins,Matthias Schmid,Ewan Hunter,Christopher J A Duncan +24 more
TL;DR: Age was the most significant risk factor for death, confirming that demographic factors in the population are a major influence on hospital mortality rates and providing important clinical context to outcome data.
Posted ContentDOI
The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centres
Emily Stephenson,Gary Reynolds,Rachel A. Botting,Fernando J Calero-Nieto,Michael D Morgan,Michael D Morgan,Zewen K. Tuong,Zewen K. Tuong,Karsten Bach,Karsten Bach,Waradon Sungnak,Kaylee B Worlock,Masahiro Yoshida,Natsuhiko Kumasaka,Katarzyna D. Kania,Justin Engelbert,Bayanne Olabi,Jarmila Stremenova Spegarova,Nicola K. Wilson,Nicole Mende,Laura Jardine,Louis C.S. Gardner,Issac Goh,Dave Horsfall,Jim McGrath,Simone Webb,Michael W. Mather,Rik G.H. Lindeboom,Emma Dann,Ni Huang,Krzysztof Polanski,Elena Prigmore,Florian Gothe,Jonathan M. Scott,Rebecca Payne,Kenneth F Baker,Aidan T Hanrath,Aidan T Hanrath,Ina Schim van der Loeff,Andrew Barr,Amada Sanchez-Gonzalez,Laura Bergamaschi,Federica Mescia,Josephine Barnes,Eliz Kilich,Angus de Wilton,A Saigal,Aarash Saleh,Sam M. Janes,Sam M. Janes,Claire Smith,Nusayhah Gopee,Caroline Wilson,Caroline Wilson,Paul Coupland,Jonathan Coxhead,Vladimir Yu. Kiselev,Stijn van Dongen,Jaume Bacardit,Hamish W King,Hamish W King,Anthony J. Rostron,A. John Simpson,Sophie Hambleton,Elisa Laurenti,Paul A Lyons,Kerstin B Meyer,Kerstin B Meyer,Marko Z Nikolic,Marko Z Nikolic,Chris Duncan,Kenneth G. C. Smith,Kenneth G. C. Smith,Sarah A. Teichmann,Menna R. Clatworthy,Menna R. Clatworthy,Menna R. Clatworthy,John C. Marioni,Berthold Göttgens,Muzlifah Haniffa +79 more
TL;DR: In this article, the authors performed single-cell RNA-sequencing coupled with analysis of cell surface proteins, providing molecular profiling of over 800,000 peripheral blood mononuclear cells from a cohort of 130 patients with COVID-19.