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Angus de Wilton
Researcher at University College London Hospitals NHS Foundation Trust
Publications - 7
Citations - 382
Angus de Wilton is an academic researcher from University College London Hospitals NHS Foundation Trust. The author has contributed to research in topics: Immune system & Haematopoiesis. The author has an hindex of 4, co-authored 7 publications receiving 85 citations. Previous affiliations of Angus de Wilton include University College Hospital & University College London.
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Journal ArticleDOI
Single-cell multi-omics analysis of the immune response in COVID-19.
Emily Stephenson,Gary Reynolds,Rachel A. Botting,Fernando J Calero-Nieto,Michael D Morgan,Michael D Morgan,Zewen K. Tuong,Zewen K. Tuong,Karsten Bach,Karsten Bach,Waradon Sungnak,Kaylee B Worlock,Masahiro Yoshida,Natsuhiko Kumasaka,Katarzyna D. Kania,Justin Engelbert,Bayanne Olabi,Jarmila Stremenova Spegarova,Nicola K. Wilson,Nicole Mende,Laura Jardine,Louis C.S. Gardner,Issac Goh,Dave Horsfall,Jim McGrath,Simone Webb,Michael W. Mather,Rik G.H. Lindeboom,Emma Dann,Ni Huang,Krzysztof Polanski,Elena Prigmore,Florian Gothe,Florian Gothe,Jonathan M. Scott,Rebecca Payne,Kenneth F Baker,Kenneth F Baker,Aidan T Hanrath,Aidan T Hanrath,Ina Schim van der Loeff,Andrew Barr,Amada Sanchez-Gonzalez,Laura Bergamaschi,Federica Mescia,Josephine Barnes,Eliz Kilich,Angus de Wilton,A Saigal,Aarash Saleh,Sam M. Janes,Sam M. Janes,Claire Smith,Nusayhah Gopee,Caroline Wilson,Caroline Wilson,Paul Coupland,Jonathan Coxhead +57 more
TL;DR: In this article, the authors performed single-cell transcriptome, surface proteome and T and B lymphocyte antigen receptor analyses of over 780,000 peripheral blood mononuclear cells from a cross-sectional cohort of 130 patients with varying severities of COVID-19.
Journal ArticleDOI
Risk of Strongyloides Hyperinfection Syndrome when prescribing dexamethasone in severe COVID-19.
Angus de Wilton,Laura E. B. Nabarro,Gauri Godbole,Peter L. Chiodini,Aileen E. Boyd,Katherine Woods +5 more
Posted ContentDOI
The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centres
Emily Stephenson,Gary Reynolds,Rachel A. Botting,Fernando J Calero-Nieto,Michael D Morgan,Michael D Morgan,Zewen K. Tuong,Zewen K. Tuong,Karsten Bach,Karsten Bach,Waradon Sungnak,Kaylee B Worlock,Masahiro Yoshida,Natsuhiko Kumasaka,Katarzyna D. Kania,Justin Engelbert,Bayanne Olabi,Jarmila Stremenova Spegarova,Nicola K. Wilson,Nicole Mende,Laura Jardine,Louis C.S. Gardner,Issac Goh,Dave Horsfall,Jim McGrath,Simone Webb,Michael W. Mather,Rik G.H. Lindeboom,Emma Dann,Ni Huang,Krzysztof Polanski,Elena Prigmore,Florian Gothe,Jonathan M. Scott,Rebecca Payne,Kenneth F Baker,Aidan T Hanrath,Aidan T Hanrath,Ina Schim van der Loeff,Andrew Barr,Amada Sanchez-Gonzalez,Laura Bergamaschi,Federica Mescia,Josephine Barnes,Eliz Kilich,Angus de Wilton,A Saigal,Aarash Saleh,Sam M. Janes,Sam M. Janes,Claire Smith,Nusayhah Gopee,Caroline Wilson,Caroline Wilson,Paul Coupland,Jonathan Coxhead,Vladimir Yu. Kiselev,Stijn van Dongen,Jaume Bacardit,Hamish W King,Hamish W King,Anthony J. Rostron,A. John Simpson,Sophie Hambleton,Elisa Laurenti,Paul A Lyons,Kerstin B Meyer,Kerstin B Meyer,Marko Z Nikolic,Marko Z Nikolic,Chris Duncan,Kenneth G. C. Smith,Kenneth G. C. Smith,Sarah A. Teichmann,Menna R. Clatworthy,Menna R. Clatworthy,Menna R. Clatworthy,John C. Marioni,Berthold Göttgens,Muzlifah Haniffa +79 more
TL;DR: In this article, the authors performed single-cell RNA-sequencing coupled with analysis of cell surface proteins, providing molecular profiling of over 800,000 peripheral blood mononuclear cells from a cohort of 130 patients with COVID-19.
Posted ContentDOI
The local and systemic response to SARS-CoV-2 infection in children and adults
Masahiro Yoshida,Masahiro Yoshida,Kaylee B Worlock,Ni Huang,Rik G.H. Lindeboom,Colin R. Butler,Natsuhiko Kumasaka,Cecilia Domínguez Conde,Lira Mamanova,Liam Bolt,Laura Richardson,Krzysztof Polanski,Elo Madissoon,Elo Madissoon,Josephine Barnes,Jessica Allen-Hyttinen,Eliz Kilich,Brendan C Jones,Angus de Wilton,Anna Wilbrey-Clark,Waradon Sungnak,Jan Patrick Prett,Elena Prigmore,Henry Yung,Henry Yung,Puja Mehta,Puja Mehta,Aarash Saleh,A Saigal,Vivian Chu,Jonathan M. Cohen,Clare Cane,Aikaterini Iordanidou,Soichi Shibuya,Ann-Kathrin Reuschl,A. Christine Argento,Richard G. Wunderink,Sean B. Smith,Taylor A. Poor,Catherine A Gao,Jane Dematte,NU Script Study Investigators,Gary Reynolds,Muzlifah Haniffa,Georgina Bowyer,Matthew L Coates,Matthew L Coates,Menna R. Clatworthy,Fernando J Calero-Nieto,Berthold Göttgens,Neil J. Sebire,Clare Jolly,Paolo De Coppi,Claire Smith,Alexander V. Misharin,Sam M. Janes,Sam M. Janes,Sarah A. Teichmann,Sarah A. Teichmann,Marko Nikolic,Marko Nikolic,Kerstin B. Meyer +61 more
TL;DR: In this paper, a healthy reference multi-omics single cell data set from children (n=30) was generated and compared with equivalent data from severe paediatric and adult COVID-19 patients (total n=27), from the same three types of samples: upper and lower airways and blood.
Journal ArticleDOI
Delayed healthcare seeking and prolonged illness in healthcare workers during the COVID-19 pandemic: a single-centre observational study
Angus de Wilton,Eliz Kilich,Zain Chaudhry,Lucy C K Bell,Joshua Gahir,Jane Cadman,Robert A Lever,Sarah Logan +7 more
TL;DR: The study revealed a concerning lack of healthcare seeking in respondents with significant red flag symptoms (severe breathlessness, hypoxia) and highlighted anosmia as a key symptom of CO VID-19 early in the pandemic, prior to this symptom being more widely recognised as a feature of COVID-19.