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Louis C.S. Gardner

Researcher at Newcastle University

Publications -  7
Citations -  564

Louis C.S. Gardner is an academic researcher from Newcastle University. The author has contributed to research in topics: Immune system & Haematopoiesis. The author has an hindex of 3, co-authored 5 publications receiving 76 citations. Previous affiliations of Louis C.S. Gardner include Newcastle upon Tyne Hospitals NHS Foundation Trust.

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Journal ArticleDOI

Single-cell multi-omics analysis of the immune response in COVID-19.

TL;DR: In this article, the authors performed single-cell transcriptome, surface proteome and T and B lymphocyte antigen receptor analyses of over 780,000 peripheral blood mononuclear cells from a cross-sectional cohort of 130 patients with varying severities of COVID-19.
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Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

Obbina Abani, +7885 more
- 03 Mar 2022 - 
TL;DR: In patients hospitalised with COVID-19, baricitinib significantly reduced the risk of death but the size of benefit was somewhat smaller than that suggested by previous trials.
Posted ContentDOI

The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centres

Emily Stephenson, +79 more
- 15 Jan 2021 - 
TL;DR: In this article, the authors performed single-cell RNA-sequencing coupled with analysis of cell surface proteins, providing molecular profiling of over 800,000 peripheral blood mononuclear cells from a cohort of 130 patients with COVID-19.
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Complexity and Diversity of Immune Responses in COVID-19

TL;DR: The adaptive host response to systemic COVID-19 is heterogeneous and complex as discussed by the authors, and a contemporary summary of these mechanisms of disease and highlights potential avenues for diagnostic and therapeutic development.