A
Anna Spada
Researcher at University of Milan
Publications - 326
Citations - 13577
Anna Spada is an academic researcher from University of Milan. The author has contributed to research in topics: Pituitary tumors & Acromegaly. The author has an hindex of 60, co-authored 322 publications receiving 12683 citations. Previous affiliations of Anna Spada include Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.
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Journal ArticleDOI
In vitro effect of dopamine on growth hormone (gh) release from human gh-secreting pituitary adenomas
TL;DR: It is hypothesize that the different in vitro responsiveness of GH-secreting pituitary adenomas to DA could be due to the presence of multiple forms of DA receptors.
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Different expression of protein kinase A (PKA) regulatory subunits in cortisol-secreting adrenocortical tumors: Relationship with cell proliferation
Giovanna Mantovani,Andrea Lania,Sara Bondioni,Erika Peverelli,C. Pedroni,Stefano Ferrero,Caterina Pellegrini,L. Vicentini,Giorgio Arnaldi,Silvano Bosari,Paolo Beck-Peccoz,Anna Spada +11 more
TL;DR: It is proposed that a high R1/R2 ratio favors the proliferation of well differentiated and hormone producing adrenocortical cells, while unbalanced expression of these subunits is not required for malignant transformation.
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Abnormal response of luteinizing hormone beta subunit to thyrotrophin-releasing hormone in patients with non-functioning pituitary adenoma
Paloma Gil-Del-Alamo,K. S I Pettersson,Katia Saccomanno,Anna Spada,Giovanni Faglia,Paolo Beck-Peccoz +5 more
TL;DR: It is suggested that the response of free β‐subunit of LH (LHβ) to TRH is the most useful in‐vivo marker of gonadotroph adenoma in patients with non‐functioning pituitary adenomas (NFPA).
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Circulating adiponectin levels and cardiovascular risk factors in acromegalic patients.
Cristina L. Ronchi,Sabrina Corbetta,Vincenzo Cappiello,P. S. Morpurgo,Claudia Giavoli,Paolo Beck-Peccoz,Maura Arosio,Anna Spada +7 more
TL;DR: Evidence is provided that, although metabolic and cardiovascular abnormalities are present in most acromegalic patients, in these subjects ApN levels are not reduced and, contrary to what is found in BMI-matched controls, do not correlate with cardiovascular risk factors.
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In vitro studies on TSH secretion and adenylate cyclase activity in a human TSH-secreting pituitary adenoma. Effects of somatostatin and dopamine
Anna Spada,Monique Bassetti,Enio Martino,G. Giannattasio,Paolo Beck-Peccoz,Alessandro Sartorio,Lucia Vallar,Lidio Baschieri,Aldo Pinchera,Giovanni Faglia +9 more
TL;DR: In this TSH-secreting pituitary adenoma surgically removed from a hyperthyroid patient showing high serum TSH levels, a normal secretory response to the inhibiting agents (GHRIH and DA) is present and different mechanisms of transduction of the GHRIh and DA signals (cAMP dependent and cAMP independent) could be operating in this tumor.