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Anna Spada
Researcher at University of Milan
Publications - 326
Citations - 13577
Anna Spada is an academic researcher from University of Milan. The author has contributed to research in topics: Pituitary tumors & Acromegaly. The author has an hindex of 60, co-authored 322 publications receiving 12683 citations. Previous affiliations of Anna Spada include Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico.
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Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection
Sabrina Corbetta,Alessandro Redaelli,Massimo Pozzi,Giorgio Bovo,Laura Ratti,Elena Redaelli,Caterina Pellegrini,Paolo Beck-Peccoz,Anna Spada +8 more
TL;DR: In this paper, the adipocyte-derived insulin-sensitizing hormone might play a protective role against hepatic fibrosis in patients with chronic hepatitis C virus (HCV) infection.
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Adequacy of current postglucose GH nadir limit (<1 μg/l) to define long-lasting remission of acromegalic disease
TL;DR: The aim of the study was to correlate GH nadir with hormonal and metabolic parameters and to confirm the adequacy of the current limit to define disease remission.
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Immunogenicity, safety and tolerability of inactivated trivalent influenza vaccine in overweight and obese children
Susanna Esposito,Claudia Giavoli,Claudia Maria Trombetta,Sonia Bianchini,Valentina Montinaro,Anna Spada,Emanuele Montomoli,Nicola Principi +7 more
TL;DR: In overweight and obese children, antibody response to TIV administration is similar or slightly higher than that evidenced in normal weight subjects of similar age and this situation persists for at least 4 months after vaccine administration in the presence of a favorable safety profile.
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Effect of Cyclic Adenosine 3′,5′-Monophosphate/Protein Kinase A Pathway on Markers of Cell Proliferation in Nonfunctioning Pituitary Adenomas
Giovanna Mantovani,Sara Bondioni,Stefano Ferrero,B. Gamba,Emanuele Ferrante,Erika Peverelli,Sabrina Corbetta,Marco Locatelli,P. Rampini,Paolo Beck-Peccoz,Anna Spada,Andrea Lania +11 more
TL;DR: Data show that in contrast with what was previously observed in transformed somatotrophs, activation of the cAMP-PKA pathway did not generate proliferative signals in tumoral cells of the gonadotroph lineage, and in a subset of tumors even exerted a tonic inhibitory effect, thus confirming a different role for the camp-mediated pathway in promoting proliferation in the pituitary.
Journal ArticleDOI
Cellular alterations in pituitary tumors.
TL;DR: It is worth noting that receptor/postreceptor alterations occurring in pituitary tumors may cause an increased action of stimulatory neurohormones with growth promoting properties as well as defective action of inhibitory inputs.